Diabetes Flashcards
main complications of diabetes
Heart disease, stroke, and hypertension; blindness; kidney disease; nervous system disorders; amputation; and pregnancy problems
Define Type 1 diabetes
Type 1 is the result of an autoimmune response that triggers the destruction of insulin-producing β cells in the pancreas and results in an absolute insulin deficiency.
Which type of diabetes is much more common, has a strong genetic component as well as a significant association with obesity and sedentary lifestyles.
DM2
Define Type 2 DM
characterized by insulin resistance (insufficient response of peripheral cells to insulin) and pancreatic β cell dysfunction (impaired insulin secretion), resulting in relative insulin deficiency.
Complications associated with chronic hyperglycemia
cardiovascular, renal, retinal, and neurological complications.
Function of insulin
Carbohydrate metabolism: Lowers blood glucose level
Protein metabolism: stimulates protein synthesis Stimulates amino acid uptake into cells; inhibits proteolysis
Lipid metabolism: maintains a fat depot and has an antiketogenic effect
Electrolyte regulation: stimulates intracellular potassium accumulation
Normal fasting blood glucose?
A fasting blood sugar level less than 100 mg/dL (5.6 mmol/L) is normal. A fasting blood sugar level from 100 to 125 mg/dL (5.6 to 6.9 mmol/L) is considered prediabetes. If it’s 126 mg/dL (7 mmol/L) or higher on two separate tests, you have diabetes.