Virology Flashcards

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1
Q

Are viruses bigger or smaller than bacteria?

A

Smaller

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2
Q

What are virions?

A

Virus particles

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3
Q

Why can’t virions grow or undergo division?

A

They lack genetic information

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4
Q

What can’t virions do?

A

Generate metabolic energy or synthesise proteins

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5
Q

What is an envelope on a virus?

A

A lipid bilayer

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6
Q

What are the 2 classes of virions?

A

Enveloped and non-enveloped

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7
Q

Components of non-enveloped virions

A

Capsomere
Nucleic acid
Capsid

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8
Q

Components of enveloped virion

A

Envelope
Capsomere
Nucleic acid

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9
Q

Role of capsid

A

Protects virion and allows it to bind to receptors using spikes

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10
Q

What are the 2 classes of capsid?

A

Icosahedral and rod-like

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11
Q

Structure of icosahedral capsids

A

60 faces formed by proteins

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12
Q

Structure of rod-like capsids

A

Protein helix around nucleic acid

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13
Q

Role of envelope

A

Allows fusion or exit with host’s cell wall

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14
Q

What is lytic infection?

A

Host cell destruction causing virus release but normally cleared quickly

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15
Q

What are viral infections?

A

Slow release of virus which is not cleared and so virus lasts long time

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16
Q

What are latent infections?

A

Lack of gene expression so virus lasts a lifetime

17
Q

Where do latent infections occur?

A

Sensory and autonomic ganglia