Milk 1 Flashcards

1
Q

When does the mammary gland develop?

A

During foetal growth, periods, pregnancy and lactation

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2
Q

What is mammogenesis?

A

Initiation of milk synthesis and secretion during and after weaning

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3
Q

Where is lactose synthesized?

A

Lactating mammary gland

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4
Q

How is milk removed from the teat?

A

Alveoli are connected to duct system which flows milk to the teat canal where it is removed

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5
Q

What are the 5 major precursors of milk production?

A

Glucose
Acetate
Beta-hydroxybutyrate
Triglyceride fatty acids
Amino acids

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6
Q

Where are proteins, amino acids and fats synthesized and removed during lactogenesis?

A

Mammalian epithelia cells (MEC)

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7
Q

What does cow feed contain?

A

Cellulose

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8
Q

How do cows digest carbohydrates?

A

Reticulo-rumen produces enzymes which hydrolyse or ferment them into volatile fatty acids

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9
Q

What is the primary energy source for the mammary gland?

A

Glucose

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10
Q

What is the whole bodies energy source in ruminants?

A

Acetate

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11
Q

What is the whole bodies energy source in monogastric?

A

Glucose

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12
Q

What is the carbon source for lactose in ruminants and monogastric?

A

Glucose

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13
Q

What is the blood glucose source for ruminants?

A

Propionate

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14
Q

What is the main carbon source for fatty acids in ruminants?

A

Acetate and butyrate

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15
Q

What is the main carbon source for fatty acids in monogastric?

A

Glucose

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16
Q

What are the main sources of glucose for milk production?

A

Propionate, gluconeogenesis, lactate and glycerol

17
Q

1st step of glucose metabolism

A

Glucose becomes glucose 6-phosphate in blood

18
Q

2nd step of glucose metabolism

A

Glucose becomes trapped within blood cells

19
Q

3rd step to glucose metabolism

A

Excess glucose converted to glycogen

20
Q

4th step of glucose metabolism

A

Glycolysis converts pyruvate to acetyl-SCoA to enter citric acid cycle

21
Q

What are the fatty acids in milk fat?

A

Long chain fatty acids (LCFA) and linoleic acid

22
Q

What are the building blocks for milk fat?

A

Volatile fatty acids (VFA)

23
Q

What improves milk fat content?

24
Q

What increases milk protein content?

A

Propionate

25
What are the precursors of acetyl CoA?
VFAs
26
1st step of carbohydrate metabolism
Acetate becomes acetyl CoA to enter TCA cycle
27
2nd step of carbohydrate metabolism
Propionate becomes succinyl CoA which becomes glucose in gluconeogenesis
28
3rd step of carbohydrate metabolism
Butyrate converted to B-hydroxybutyrate across rumen wall then into acetyl CoA
29
What are the 5 precursors for milk fat?
Glucose Acetate B-hydroxybutyrate Triglycerides Lipoproteins
30
How are milk lipids produced?
Absorbed from blood or synthesised from acetate
31
Where are B-hydroxybutyrate and acetate absorbed?
Basolateral membrane
32
Where are triglycerides synthesised?
Cytoplasm of mammary epithelial cells
33
How are casein, alpha-lactalbumin and beta-lactoglobulin synthesised?
From amino acids in mammary epithelial cells