Viral Infections Flashcards

1
Q

Virus that can cause gastroenteritis

A
Rotavirus 
Adenovirus
Calicivirus
Astrovirus 
Small round virus like object (SRVs)
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2
Q

Viral gastroenteritis mode of transmission

A

Fecal oral

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3
Q

Virus which cause disease at distant site from GIT

A

HAV/ HEV
Polio
Lassavirus
Coxsackie virus

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4
Q

Rotavirus classification and morphology

A

Non enveloped
DsRNA
Wheel like appearance

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5
Q

Most Common cause of severe infantile diarrhea

A

Rotavirus

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6
Q

Rotavirus species that infect humans

A

A
B
C

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7
Q

Major cause of severe dehydrating Gastro enteritis in young humans

A

Group A rotavirus

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8
Q

Pathogenesis of rotavirus

A

Ingestion -> infect cells of the villi of the small intestine -> damaged cells replaced by non absorbing immature crypt cells -> damaged cells may sloug into lumen of intestine -> diarrhea due to impaired sodium and glucose absorption -> excreted in stool

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9
Q

Children Rotavirus infections clinical presentation

A

Vomiting
Watery diarrhea
Fever
Abdominal pain

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10
Q

Sympyoms on adults , strong or mild ?

A

Mild

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11
Q

Are there rotavirus Vaccines ?

A

Still being evaluated

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12
Q

Diagnosis rests of virus in stool collected during illness

A

Immune electron microscopy

Particle agglutination

ELISA

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13
Q

Adenovirus characteristics

A

Non enveloped dsDNA

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14
Q

Adenovirus serotypes involved in gastro in children

A

40 & 41

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15
Q

Pathogenesid and lab of adenovirus

A

Same as rotavirus

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16
Q

Calicivitus two families

A

Norovirus

Sapovirus