Viral Hepatitis

Question 1

Match the following forms of hepatitis with the appro-
priate description (a-d), using each answer only once.

1. _______ Acute hepatitis
2. _______ Fulminant acute hepatitis
3. _______ Subclinical hepatitis without jaundice
4. _______ Chronic hepatitis
   a. This rare form is associated with hepatic failure.
   b. Typical form of hepatitis with associated jaundice
   c. Probably accounts for persons with serum antibodies
   but no history of hepatitis
   d. Accompanied by hepatic inflammation and necrosis

Answer 1

1. b
2. a
3. c
4. d

Question 2

Match the following (use an answer only once).
5. _______ Hepatitis A
6. _______ Hepatitis B
7. _______ Hepatitis D
8. _______ Hepatitis C
a. Intact virus is the Dane particle
b. Transmission by both parenteral and nonparenteral
routes
c. Requires HBV as a helper
d. Most common form of hepatitis

Answer 2

5. d
6. a
7. c
8. b

Question 3

Match the following (use an answer only once).
9. _______ Hepatitis A
10. _______ Hepatitis B
11. _______ Delta agent
12. _______ Hepatitis C
a. Should receive immune globulin intramuscularly
after exposure
b. Defective or incomplete RNA virus
c. Has an epidemiology similar to that of HAV
d. Previously called Australia antigen

Answer 3

9. a
10. d
11. b
12. c

Question 4

Match the following serologic markers with the
appropriate description.
13. _______ HBsAg
14. _______ HBeAg
15. _______ Anti-HBc
16. _______ Anti-HBe
17. _______ Anti-HBs
a. Indicator of recent HBV infection may be only
serologic marker during the window phase
b. Found in the serum of some patients who are
HBsAg positive; marker for level of virus, infectivity
c. A serologic marker of recovery and immunity
d. Initial detectable marker found in serum during
incubation period of HBV infection
e. In the case of acute hepatitis, the first serologic
evidence of the convalescent phase

Answer 4

13. d
14. b
15. a
16. e
17. c

Question 5

Of patients in the United States with chronic hepatitis B,
_______ of them acquired the virus in childhood.
a. Less than 20%
b. 20% to 30%
c. 30% to 40%
d. More than 40%

Answer 5

b. 20% to 30%

Question 6

The rate of posttransfusion hepatitis C decreased to
_______ after the introduction of serologic testing in the
screening of blood donors.
a. Less than 1%
b. 5%
c. 10%
d. 15%

Answer 6

d. 15%

Question 7

Match the following forms of hepatitis with the
correct average incubation time.
20. _______ Hepatitis A
21. _______ Hepatitis B
22. _______ Hepatitis C
a. 5 days
b. 25 days
c. 50 days
d. 75 days
e. 150 days

Answer 7

20. b
21. d
22. c

Question 8

Which form of hepatitis does not have a chronic form of
the disease?
a. Hepatitis A
b. Hepatitis B
c. Hepatitis C

Answer 8

a. Hepatitis A

Question 9

Another name for hepatitis B infection is:
a. Infectious hepatitis
b. Long incubation hepatitis
c. Australia antigen
d. Dane particle

Answer 9

b. Long incubation hepatitis

Question 10

The most frequent clinical response to hepatitis B virus is:
a. Jaundice within 75 days
b. Asymptomatic infection
c. Subclinical infection
d. Both b and c

Answer 10

d. Both b and c

Question 11

The first laboratory screening test of donor blood was for
the detection of:
a. HBc
b. HBsAg
c. HBe
d. Anti-HBe

Answer 11

a. HBc

Question 12

Which surface marker is a reliable marker for the
presence of high levels of hepatitis B virus (HBV ) and a
high degree of infectivity?
a. HBeAg
b. HBsAg
c. HBcAg
d. Anti-HBsAg

Answer 12

b. HBsAg

Question 13

The only serologic marker during the anti-core window
period of hepatitis B (the time between disappearance of
detectable HBsAg and appearance of detectable anti-
HBs) may be:
a. Anti-HBs
b. Anti-HBc
c. Anti-HBe
d. HBsAg

Answer 13

b. Anti-HBc

Question 14

Which of the following is a characteristic of the delta agent?
a. Is a DNA virus
b. Usually replicates only in HBV-infected hosts
c. Infects patients who are HBcAg positive
d. Is frequently found in the United States

Answer 14

b. Usually replicates only in HBV-infected hosts

Question 15

Which of the following viruses is rarely implicated in
transfusion-associated hepatitis?
a. Hepatitis A
b. Hepatitis B
c. Hepatitis C
d. Cytomegalovirus

Answer 15

a. Hepatitis A

Question 16

In health care workers, the risk of contracting hepatitis C
is _______the risk of contracting AIDS.
a. Lower than
b. Higher than
c. The same as
d. Not something to worry about compared to

Answer 16

b. Higher than

Question 17

The specific diagnostic test for hepatitis C is:
a. Absence of anti-HAV and anti-HBsAg
b. Increase in liver serum enzyme levels
c. Detection of non-A, non-B antibodies
d. Anti-HCV

Answer 17

d. Anti-HCV

Question 18

The earliest detectable serologic marker of acute hepatitis
C is:
a. Anti-HCV
b. Anti-HBc and liver serum enzyme abnormalities
c. HCV-RNA
d. Anti-HBs and anti-HBc

Answer 18

c. HCV-RNA

Question 19

Primary hepatitis viruses are given this name because
they primarily attack:
a. A variety of body systems
b. The liver
c. The skin
d. The nervous system

Answer 19

b. The liver

Question 20

Hepatitis A has all the following characteristics except:
a. DNA virus
b. Short-incubation hepatitis
c. Crowded, unsanitary conditions as a risk factor
d. Rare occurrence of transfusion acquisition

Answer 20

a. DNA virus

Question 21

The Australia antigen is now called:
a. Dane particle
b. Long-incubation hepatitis
c. Hepatitis B surface antigen (HBsAg)
d. Hepatitis B core antigen (HBcAg)

Answer 21

c. Hepatitis B surface antigen (HBsAg)

Question 22

Which category has the highest incidence of acute
hepatitis C?
a. Low socioeconomic status
b. Dialysis
c. Transfusion
d. Illegal drug use

Answer 22

d. Illegal drug use

Question 23

Which category has the lowest incidence of acute
hepatitis C?
a. Sexual, household
b. Dialysis
c. Drug abuse
d. Transfusion

Answer 23

d. Transfusion

Question 24

Match each form of hepatitis to the appropriate mode
of transmission. (You may use an answer more than
once.)
45. _______ Hepatitis A
46. _______ Hepatitis B
47. _______ Hepatitis C
48. _______ Hepatitis E
a. Fecal-oral
b. Parenteral
c. Parenteral and nonparenteral

Answer 24

45. a
46. b
47. c
48. a