Vaccines

Question 1

The Center for Biologics Evaluation and Research
CBER regulates:
a. Laboratory safety
b. Vaccine products
c. Personnel qualifications
d. Research grants

Answer 1

b. Vaccine products

Question 2

Pathogens adapted for biological warfare include:
(1) Smallpox
(2) Bacillus anthracis
(3) Chickenpox
(4) Q fever
a. 1, 2, 3
b. 1, 2, 4
c. 2, 3, 4
d. 1, 3, 4

Answer 2

b. 1, 2, 4

Question 3

Vaccines can be divided into _________ vaccines.
a. Live, attenuated
b. Nonreplicating
c. Naked DNA
d. Both a and b

Answer 3

d. Both a and b

Question 4

To meet FDA requirements, a vaccine must:
a. Produce protective immunity with only minimal side
effects.
b. Be immunogenic enough to produce a strong and
measurable immune response.
c. Be stable during its shelf life.
d. All of the above.

Answer 4

d. All of the above.

Question 5

The earliest host response to vaccination is a(n):
a. Innate immune response
b. Memory response
c. Anamnestic response
d. Both a and b

Answer 5

a. Innate immune response

Question 6

Match the following:
6. ____ Preventive HIV vaccine
7. ____ Therapeutic HIV vaccine
a. Given to HIV-negative individuals
b. For HIV-positive patients to improve their immune
system to prevent progression to AIDS

Answer 6

6. a
7. b

Question 7

Match the following (use an answer only once):
8. ____ Anthrax vaccine
9. ____ Cytomegalovirus CMV vaccine
10. ____ Hay fever vaccine
11. ____ Human papillomavirus (HPV) vaccine
12. ____ Influenza vaccine
a. Protection against bioterrorism
b. Protection against cervical cancer
c. Not available for preventing congenital infection
d. DNA-based vaccine
e. Annual vaccination required

Answer 7

8. a
9. c
10. d
11. b
12. e

Question 8

Match the following:
13. ____ Leukemia vaccine
14. ____ Polio vaccine
15. ____ Smallpox vaccine
a. Has reduced disease by 99%
b. Successful in cats
c. Given to high-risk individuals

Answer 8

13. b
14. a
15. c