Viral GI (lec 4)

Question 1

Filterable Agent means?

Answer 1

able to pass thru fine pore filters

Question 2

Viruses replicate how?

Answer 2

use hosts’ metabolism
assembly-line process
no binary fission

Question 3

Lytic viral-host interaction is?

Answer 3

rapid replication of new virions lyse host

Question 4

Non-lytic viral-host interaction?

Answer 4

virus remains a/w host but genes mostly unexpressed (called prophages)

stable/long-term relationship (persistent infection)

Question 5

Latent infections?

Answer 5

(herp)
intermittent acute episodes of virus prdxn

absence of virus particle and limited synthesis b/w episodes

Question 6

Chronic infections are?

Answer 6

(hep B)
nonlytic prdxn of virus,
particle always present

Question 7

Transforming infections?

Answer 7

(HPV)

host cell altered to cancer cells

Question 8

Viral Gastroenteritis (VGI) sxs?

Answer 8

N/V/D
malaise
myalgia
HA

Question 9

VGI replication happens where?

Course?

Answer 9

in small intestine epithelial cells
up to 48hrs incubation
infection runs 3-5 days

Question 10

VGI diagnostic tests?

Answer 10

Rotazyme = +antigens

Question 11

VGI tx?

Answer 11

oral rehydration

Question 12

VGI epidemiology?

Answer 12

Rotavirus (infants)

Norovirus (fecal-contamination)

Question 13

VGI prevention?

Answer 13

Rota vaccine

no Noro vaccine

Question 14

Rotavirus action?

Answer 14

infect small int villi enterocytes

disrupt osmotic fxn

Question 15

Rotavirus infection pattern?

Answer 15

follow predictable pattern

winter breakouts

Question 16

Enteric Adenoviruses are?

Cause?

Diagnosed?

Answer 16

DS DNA

extended period infant D

imunoassay

Question 17

Caliciviruses are?

Cause?

Answer 17

Noroviruses
a/w food, water
very resistant

mild, self-limiting D/V

Question 18

Stages of viral replication?

Answer 18

uncoating ->
use host replication system ->
assembly ->
maturation ->
release