VIH Flashcards

1
Q

Clasificación OMS para VIH Segun CD4

A

-CD4 >_ 500/mm3: A1, B1, C1
-CD4 200-499 mm3: A2, B2, C2
-CD4 <200 mm3: A3, B3 y C3

Letra A: asintomatico o Aguda (Sx retroviral aguda) Fiebre, diarrea, linfadenopatía

Letra C: SIDA
-Candidiasis esofagica, toxoplasmosis cerebral, retinitis por CMV, neumonia por P. Jirovecci, Histoplasmosis extrapulmonar, Coccidioides extrapulmonar, Isospora o criptosporiodosis crónica, Kaposi, Linfomas, cancer cervicouterino invasivo

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2
Q

Inhibidores de transcriptasa reversa análogo de nucleósidos

A

Abacavir (ABC)
Emtricitabina (FTC)
Lamivudina (3TC)
Zidovudina (AZT-ZDV)

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3
Q

Inhibidores de transcriptasa reversa analogos de nucleotidos

A

Tenofovir
-Disoproxil TDx .- causa ER y osteoporosis
-Alafenamida TAF.- más seguros

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4
Q

Inhibidores de transcriptasa reversa no nucleosidos

A

-Doravirina (DOR) mejor y más seguro
-Efavirenz (EFV).- efectos secundarios terrores nocturnos, teratogenico (defectos del tubo neural)
-Nevirapina (NVP)
-Rilpivirina (RPV)

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5
Q

Inhibidor de proteasa

A

-Atazanavir (ATV)
-Darunavir (DRV)
-Indinavir (IDV)
-Lopinavir (LPV)
-Ritonavir (RTV)

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6
Q

Inhibidor integrasa

A

-Bictegravir
-Dolutegravir
-Raltegravir
-Elvitegravir

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7
Q

Primera y segunda línea tratamiento VIH

A

1° Tenefovir + Emtricitabina + Bictegravir
2° Abacavir + lamivudina + Dolutegravir

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