Vestibular System Flashcards

1
Q

Labyrinth?

A

Inner Ear!

Protected by the temporal bone

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2
Q

Organs of the Labyrinth?

A
  1. Semi-circular canals
    o stimulated by ANGULAR acceleration
    o gives signal of approx. angular velocity
  2. Otolith organs
    o i.e. Saccule & Utricle
    o stimulated by LINEAR acceleration and GRAVITY force
    o gives signal of head acceleration & tilt
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3
Q

Ampulle?

A

Semi-circular canals

3 canals at the end of which you find the ampulla

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4
Q

What are the signals received by the Labyrinth used to do?

A
  1. Control BALANCE
    o dysfunction leads to ataxia
  2. Provide SPATIAL REFERENCE for other motor actions
    o dysfunction leads to ataxia
  3. Provide COMPENSATORY REFLEXES
    o total loss dysfunction leads to oscillopsia (objects oscillate)
    o unilateral loss dysfunction leads to nystagmus
  4. Provide PROPRIOCEPTION
    o dysfuntion leads to dizziness
  5. Tune CVS for RE-ORIENTATIONS
    o dysfunction leads to dizziness

Unusual stimulation of the balance organs provokes motion sickness!

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5
Q

What 3 types can vestibular disorders be?

A
  1. Structural
    o destructive OR irritative disease
  2. Functional
    o mis-interpretation of sensory input
    o mal-adaptation
    o loss of rules of correspondence
  3. Both
    o structural disorder provoking chronic dysfunction
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6
Q

Disorders of the vestibular system?

A

Include:

  1. Vertigo - false perception of movement in space
  2. Vestibular ataxia - instability of gait & posture
  3. Vestibular nystagmus - UNILATERAL vestibular lesion
  4. Oscillopsia - BILATERAL vestibular lesion
  5. Motion sickness - loss of co-ordination on directional reorientation, oversensitivity to visual motion in the envrionment
  6. Acute phase of vestibular loss - slight impairment of orthostatic control = severe nausea and vomiting
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7
Q

Otolith Organs?

A

2 Otolith Organs

  1. Utricle - senses movement in the HORIZONTAL plane
  2. Saccule - senses movement in the VERTICAL plane
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8
Q

Anatomy of the Otolith organs?

A

o Otoconia

  • layer of CaCO3 on top of gelatinous layer
  • heavy SO movements of the head DISPLCE the otoconia = pulls the hair cells

There is ONE KINOCILIUM per hair cell
o movements TOWARDS it = stimulate cell
o movements AWAY from it = inhibit cell

These cells are OMNI-DIRECTIONAL

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9
Q

Anatomy of semi-circular canals?

A

3 semi-circular canals
o each join into an ampulla - contains a CAPULA full on hair bundles

Displacement of endolymph in the canals will MOVE the CAPULA
o = fire off APs from the hair cells

CONSTANT tonic firing @ rest

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10
Q

Linear acceleration in the otolith organs and semi-circular canals?

A

Organ - MOVE the heavy otoconia layer

S-C Cs - produce EQUAL FORCE from eahc side of the capula SO NO net movement
remember stimulated by angular movement

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11
Q

What happens when the head turns left?

A
  1. Head turns left
  2. Movement towards kinocilium in the horizontal canal in the left ear
    o BUT away from kinocilium in right ear
  3. SO DP is left ear
    o Hyperpolarisation in the right ear
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12
Q

Vestibular-Ocular Reflex

A

SUPERIOR & MEDIAL vestibular neurons project to motor nuclei supplying the extraocular muscles!

  1. Axons ascend in MLF (medial longitduinal fusciculus)
  2. Excite the ipsilateral oculomotor (CN III) nucleus
  3. Also excite the contralateral abducens (CN VI) nucleus
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13
Q

VOR?

A

The vestibulo-ocular reflex (VOR) is a reflex, where activation of the vestibular system of the inner ear causes eye movement.

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14
Q

Head-movements to the left in terms of VOR?

A

Eyes rotate to the R
and
SACCADE (a rapid movement of the eye between fixation points) to the L

VOR acts to maintain gaze on a selected target

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15
Q

Oscillopsia?

A

Loss of vestibular function impairs eye stabilisation during rapid head movement

o this is as the VOR is the only mechanism to drive fast compensatory reflex

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16
Q

How do you diagnose Oscillopsia?

A

‘Head shaking test’ - head is oscillated and the eyes monitored

17
Q

Bilateral and unilateral loss in oscillopsia?

A

BILATERAL

o eyes will be TAKEN OFF TARGET by head swing
o MULTIPLE catch-up saccades will be made to regain target

UNILATERAL

o detected by discrete fast swings of head
o fast swing to GOOD SIDE = eye will REMAIN on target
o fast swing to LESIONED SIDE = result in CATCH-UP saccade

18
Q

Bilateral & unilateral Vestibular Ataxia?

A

BILATERAL

o mild gait ataxia
o worse at speed, when negotiating rough ground OR vision is reduced

UNILATERAL

o tendency for the body and head to lean and fall to LESIONED side
o becomes pronounced in difficulat balancing situation

19
Q

VSR tracts?

A

Vestibulo-Spinal Reflex

  1. Lateral V-S Tract
    - descends ipsilaterally
    - in ventral funiculus of SC
    - axons terminate in LATERAL ventral horn
    - influences motor neurons to the limbs
  2. Medial V-S Tract
    - descends bilaterally
    - in MLF (medial longtiudinal fusciculus) towards CERVICAL & THORACIC SC
    - axons terminate in MEDIAL ventral horn
    - influence motor neurons to neck & back

Lesions to these tracts can therefore bring about hypotension, respiratory dysrhythmia, HR, nausea and vomiting (motion sickness)