Vesiculobullous & Immune Disease 2 Flashcards
1
Q
what is pemphigoid?
A
Relatively common:
thick walled blisters, sub epithelial antibody attack causing sub-epithelial split at junction of HEMIDESMOSOMES at CT junction
2
Q
What is the pattern of PEMPHIGOID on immunofluorescence?
A
LINEAR Staining along basement membrane
3
Q
how do you manage pemphigoid?
A
steroids & immune modulating drugs (azathioprine)
4
Q
What is pemphigus?
A
INTRAEPITHELIAL blistering, uncommon before age of 50
Can be found on skin & mucosa
Blisters -> burst -> spread
5
Q
what it the immunofluorescence pattern of PEMPHIGUS?
A
basket weave pattern
6
Q
what type of pemphigus affects the mucosa & skin?
A
Pemphigus Vulgaris
7
Q
A
