Vesiculobullous & Immune Disease 1

Question 1

what are examples of LOCAL DISEASE in immunological oral disease?

Answer 1

• Aphthous ulcers
• Lichen Planus
• Orofacial Granulomatosis

Question 2

what are examples of SYSTEMIC DISEASE with local effects in immunological oral disease?

Answer 2

• Erythema Multiforme
• Pemphigus
• Pemphigoid
• Lupus erythematosus
• Systemic sclerosis
• Sjogren’s syndrome

Question 3

what is erythema multiforme?

Answer 3

immunogenic related skin & mucosa irritation/lesions with variable orofacial involvement

(Skin - target lesions)
(mucosa - ulcers)

Question 4

what can cause erythema multiforme?

Answer 4

medicines, herpes simplex,

Question 5

where on the orofacial region does erythema multiforme usually present?

Answer 5

Lips & anterior part of mouth

Question 6

for oral lesions of erythema multiforme, what treatment would you provide a pt?

Answer 6

Urgent medical therapy:
- systemic steroids
- systemic aciclovir

Encourage fluid intake (may need IV fluid if unable to drink)

Encourage analgesia

if RECURRENT;
- consider prophylactic aciclovir
- allergy test - possible trigger?

Question 7

what is angina bullosa haemorrhagica?

Answer 7

most common oral blister condition

sudden appearance of blood filled blister in the mouth (Buccal mucosa & soft palate - most common)

usually painless, no scarring

Use Chx if you wish

Question 8

how do you manage angina bullosa haemorhaggica?

Answer 8

No tx available at present

reassure pt that disease is benign

explain known triggers & course of disease