Ventricular Systolic Function Flashcards
What are the ventricle systolic functions? (3)
- Systemic - LV pump blood to body
- Pulmonary - RV pump blood to lungs
- Adequate perfusion
What is the basis of systolic dysfunction?
Inability to contract
What produces ventricular systole?
Depolarization of the ventricles followed by contraction
How does contraction affect pressure in the ventricles?
Increases it
What are the phases of systole?
- IVCT (Isovolumic Contraction Time) - Valves closed pressure building
- Ventricular Ejection - AV valves closed, semi-lunar open due to pressure gradient
When does IVCT occur?
Onset of QRS
What are the intracardiac pressures for the LV?
Sys = 120 mmHg Dia = 10 mmHg
What are the intracardiac pressures for the LA?
Mean = 10 mmHg
What are the intracardiac pressures for the RV?
Sys = 25 mmHg Dia = 4 mmHg
What are the intracardiac pressures for the AO?
Sys = 120 mmHg Dia = 70 mmHg Mean = 85 mmHg
What are the intracardiac pressures for the PA?
Sys = 25 mmHg Dia = 10 mmHg Mean = 16 mmHg
Describe the sequence of the pressure/volume relationship through the cardiac cycle in the LV/RV (9 steps)
- Depolarization of LV/RV
- Contraction
- Increased pressure
- Pressure exceeds AO/PA
- AO/PA open
- Ejection
- Decreased pressure
- AO/PA close
- Pressure falls until MV/TV open
What is the pressure-volume loop?
A display of the pressure/volume relation ship on a graph where pressure climbs during contraction (IVC), equalizes during ejection(systole), falls during relaxation (IVR) and equalizes during Diastole.
What is the difference between the pressure/volume loop in the RV and LV?
In the LV the loop is square and in the RV it is triangular due to lower pressures, lower impedance of the vascular bed and flow continuing to enter the PA after the peak pressure is reached in the right heart.
What is preload?
The muscle stretch due to volume increase at the end-diastole before contraction.
What is afterload?
The tension/load that the LV must eject or overcome before fiber shortening occurs
How can we measure preload?
We can only estimate it by using:
- LVEDV or RVEDV
- LVEDP or RVEDP
- LA or RA Pressure
How are preload, EDV and SV all related?
They are all directly related.
An increase in preload will increase the end-diastolic volume which will increase the stroke volume.
What is stroke volume?
The amount of blood pumped out of the LV or RV in one systolic contraction.
What factors affect afterload? (3)
- Ventricular volume
- Vascular resistance (blood pressure in the Ao or PA)
- Wall thickness
Which ventricle is more resistant to afterload?
The RV
How is afterload related to ESV and SV?
Changes in afterload affect the ability of the ventricles to contract therefore if the afterload increases, the SV decreases and the ESV increases (blood left in ventricle).
What is another name for inotropy?
Contractility
What does inotropy/contractility mean?
The strength of the cardiac muscle and its ability to shorten with contraction.