Ventilation and Acidosis/ Alkalosis Flashcards
Acid - Base balance equation
CO2 + H2O <-> H2CO3 <-> H+ + HCO3-
How does the equation shift give examples
CO2 increases shifts right and HCO3/H+ increase then shifts left
What is the respiratory component of acid/base equation
CO2 controlled by alveolar ventilation
what is the metabolic component of the acid/base equation
H+/ HCO3 controlled by renal excretion
Define Pulmonary Acid/base balance
CO2 regulated by tidal volume/ respiration rate
How long does Pulmonary acid/base balance take
minutes to hours
how effective is pulmonary acid/base balance
50-75% and does not completely normalize ph
Describe decrease in PH relative to pulmonary acid/base balance
Increase in tidal or respiratory rate and CO2 is exhaled and blood pH increases
Describe Renal acid/base balance
Kidneys control pH by adjusting the amount of HCO3- by excreted or reabsorbed
reabsorption HCO3- = to excretion of free H+
How long does renal acid/base balance take
hours to days
When is Acidaemia
Serum pH <7.35
When is Alkalaemia
Serum pH >7.45
What is acidosis
acid accumulation or alkali loss
what is alkalosis
alkali accumulation or acid loss
What is respiratory acidosis/alkalosis
Changes in PCO2