Ventilation and Acidosis/ Alkalosis Flashcards

1
Q

Acid - Base balance equation

A

CO2 + H2O <-> H2CO3 <-> H+ + HCO3-

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2
Q

How does the equation shift give examples

A

CO2 increases shifts right and HCO3/H+ increase then shifts left

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3
Q

What is the respiratory component of acid/base equation

A

CO2 controlled by alveolar ventilation

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4
Q

what is the metabolic component of the acid/base equation

A

H+/ HCO3 controlled by renal excretion

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5
Q

Define Pulmonary Acid/base balance

A

CO2 regulated by tidal volume/ respiration rate

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6
Q

How long does Pulmonary acid/base balance take

A

minutes to hours

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7
Q

how effective is pulmonary acid/base balance

A

50-75% and does not completely normalize ph

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8
Q

Describe decrease in PH relative to pulmonary acid/base balance

A

Increase in tidal or respiratory rate and CO2 is exhaled and blood pH increases

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9
Q

Describe Renal acid/base balance

A

Kidneys control pH by adjusting the amount of HCO3- by excreted or reabsorbed
reabsorption HCO3- = to excretion of free H+

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10
Q

How long does renal acid/base balance take

A

hours to days

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11
Q

When is Acidaemia

A

Serum pH <7.35

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12
Q

When is Alkalaemia

A

Serum pH >7.45

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13
Q

What is acidosis

A

acid accumulation or alkali loss

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14
Q

what is alkalosis

A

alkali accumulation or acid loss

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15
Q

What is respiratory acidosis/alkalosis

A

Changes in PCO2

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16
Q

What is metabolic acidosis/alkalosis

A

changes in HCO3-

17
Q

What is single acid-base disorder (compensation)

A

One disturbance with compensatory mechanism

18
Q

What is Mixed or complex (compensation)

A

two or more primary disturbances

19
Q

Describe respiratory acidosis

A

Decrease in minute ventilation(hypoventilation) which causes increased CO2 in body >40mmHG(hypercapnia)
Increased CO2 shift equation and increase H+ ions so PH decreases

20
Q

Describe respiratory alkalosis

A

Increase in minute ventilation(hyperventilation)
decreased CO2 in body <38mmhg(hypocapnia)
decreased CO2 shift equation and decrease H + ions so PH increases

21
Q

Describe metabollic Acidosis

A

Gain of H+ or loss of HCO3- <24mEQ/L
Causes a decrease in PH

22
Q

Describe metabolic alkalosis

A

Loss of H+ or Gain of HCO3- >28mEq/L
Causes a increase in PH

23
Q

What is Increase in CO2 and Decrease PH

A

respiratory acidosis

24
Q

What is decrease CO2 and increase PH

A

respiratory Alkalosis

25
Q

What is decrease HCO3 and decrease PH

A

Metabolic acidosis

26
Q

What is increase HCO3 and increase PH

A

Metabolic alkalosis

27
Q

What is Shock

A

A condition of acute peripheral circulatory failure due to derangement of circulatory control or loss of circulating fluid. It is marked by hypotension, coldness of the skin and tachycardia

28
Q

What happens to cells in shock

A

function is affected and left untreated cells may be damaged and die and main process in under perfusion of vital tissues and also inadequate blood supply so increase anaerobic respiration so increase CO2 and lactate

29
Q

Name types of shock

A

Hypovolemic, distributive, cardiogenic and obstructive

30
Q

What types are primary decrease in cardiac output (shock)

A

Cardiogenic and obstructive

31
Q

Define Hypovolemic

A

low circulating blood volume

32
Q

Give Hypovolemic shock causes

A

Loss of blood-trauma
Body fluids-
skin - burns and sweating
GI tract- vomiting and diarrhea
Kidneys- adrenal insufficiency

33
Q

Define Distributive (shock)

A

Vasodilation

34
Q

Examples of distributive (vasodilation)(shock)

A

Anaphylaxis
Bacterial infection (septic shock)
severe injury to spinal cord
medicine/poisons