Vent Pharmacology - Neuromuscular Blocking Agents

Question 1

Match the following Neuromuscular Blockades with their correct Mechanism of Action

Answer 1

Question 2

Which of the following is true regarding potentiation of NDMB effects?

Answer 2

Hypothermia will prolong duration

Question 3

Elderly and pediatric patients require lower doses of NDMB agents.
True or False?

Answer 3

False

Question 4

Which of the following is true regarding of Succinylcholine interactions?

Answer 4

Liver disease alters pseudocholinesterase and increases duration of action

Question 5

Which of the following NDMB cause Histamine mediated cardiovascular effects?

Answer 5

Atracurium

Question 6

Select the contraindications to Succinylcholine use:
Select ALL that apply.

Answer 6

Malignant Hyperthermia
Severe burns
Severe trauma
Angle-closure glaucoma
Pathology causing denervation

Question 7

Precaution should be taken using Succinylcholine in Pediatrics due to risk of bradycardia. True or False?

Answer 7

true

Question 8

Which of the following is true regarding elimination of NMBA ?

Answer 8

Cisatracurium clearance is not affected by renal or liver disease

Question 9

Which of the following is true regarding Neuromuscular blocking agents and denervated Junctions? Select ALL that apply.

Answer 9

Immature junctions are more sensitive to depolarizing agents
Immature Junctions have a 10-fold increase in mean channel open time increasing Potassium leak
Percentage of burns is not correlated with severity of hyperkalemic response
Highest risk for hyperkalemia with Succinylcholine use in burns is within the first 24 hours