Cardiac Pharmacology - Vasopressor/Inodilators Flashcards
Due to the below effects, Dobutamine has variable effects on mean arterial and blood pressure:
Mainly beta adrenergic effects with little alpha adrenergic effects
Phenylephrine shows primarily alpha effects with little to no beta effects, this results in:
Venous and arterial vasoconstriction with no effect on myocytes
Consequence of Phenylephrine’s strict A1 agonism include:
Bradycardia
In the setting of cardiac dysfunction, Phenylephrine can increase preload more than afterload, resulting in increased right heart strain. True or False?
False
The systemic action of Dopamine is mediated by which of the following receptors:
Select all that apply.
Alpha
Beta
All Dopamine Receptors
Dopamine’s activation of the D1 receptors on smooth muscle, the proximal renal tubule, and cortical collecting duct increase diuresis regardless of the patients volume status. True or False?
True
All of the following vasopressors are proarrhythmic, except:
Vasopressin
Please match the Following V receptors with their action.
V1 - Vasoconstriction
V2 - Plasma volume and osmolality control
V3 - ACTH release
Which of the following describes Vasopressin’s actions to improve hemodynamics in septic shock:
Vasopressin blocks potassium-sensitive ATP channels, restoring vascular tone
Combining Norepinephrine and Vasopressin can result in:
Digital Ischemia
Which of the following is true regarding the metabolism of Dobutamine
Dobutamine steady state is rather predictable with IV infusion
Dobutamine exerts which of the following effects on vasculature:
Reduction in pulmonary artery pressure
Which of the following is true regarding vasopressor affinity?
Epinephrine has a higher affinity for Beta2 than salbutamol
Epinephrine shows which of the following cardiovascular effects:
Select all that apply.
Increase preload
Decrease afterload
Increase blood flow to skeletal muscle
Epinephrine causes which of the following metabolic derangements?
Hyperglycaemia
