Venous ulcers (CV) Flashcards

1
Q

What are venous ulcers?

A

Large, shallow, sometimes painful ulcers usually found superior to the medial malleoli

Break in skin below knee which has not healed within 2 weeks, occurring in presence of venous disease

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2
Q

What are venous ulcers caused by?

A
  • incompetent valves in lower limbs leading to venous stasis and ulceration
  • sustained venous hypertension
  • results from chronic venous insufficiency (venous stasis) due to:
    1. venous valve incompetence
    2. impaired calf muscle pump
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3
Q

What are the clinical features of venous ulcers? (4)

A
  • frequently occur just above the medial malleolus
  • typically painless/mild pain - less painful when elevated
  • shallow ulcers with irregular borders
  • itchy
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4
Q

What might you see on examination of venous ulcers? (7)

A
  • phlebitis
  • lipodermatosclerosis - painful hardened right skin, inverted champagne bottle sign if severe
  • haemosiderin deposition - dark colour
  • excessive exudate
  • pitting oedema - rule out CKD, heart failure
  • venous eczema - itchy, red, scaly and/or flaky skin, may have blisters, crust on surface
  • atrophie blanche - star-shaped, ivory-white, depressed, atrophic scars with surrounding pigmentation
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5
Q

What are some features of venous insufficiency (therefore seen in venous ulcers)? (4)

A
  • oedema (pitting)
  • brown pigmentation - haemosiderin deposition
  • lipodermatosclerosis - hardening of skin
  • eczema
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6
Q

What are some risk factors for venous ulcers? (7)

A
  • obesity
  • immobility
  • increasing age
  • varicose veins
  • history of DVT
  • previous injury to leg
  • abdominal tumours - compressing iliac veins, AV malformations, major joint replacement
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7
Q

What are the first-line investigations for venous ulcers? (2)

A
  • duplex ultrasound of lower limbs
  • ankle brachial pressure index (ABPI) - to exclude arterial ulcer, normal range 0.8-1.3
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8
Q

For venous ulcers, what do we do if ankle bronchial pressure index (ABPI) <0.8?

A

Do NOT apply a pressure bandage as this could worsen the ulcer

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9
Q

When is biopsy performed for venous ulcer?

A

In any non-ischaemic wound that fails to improve after 3 months of treatment - if possibility of Marjolin’s ulcer

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10
Q

When are swabs for microbiology done for venous ulcer?

A

If signs of infection

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11
Q

What blood abnormalities can delay healing of venous ulcers?

A
  • FBC - presence of anaemia
  • U&Es - high urea = dehydration
  • low albumin = protein loss and malnutrition
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12
Q

How can we monitor progression of venous ulcers?

A

Measure surface area of ulcer to allow monitoring of progression

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13
Q

What are some differential diagnoses for venous ulcers? (6)

A
  • peripheral artery disease
  • rheumatoid arthritis (vasculitic)
  • systemic vasculitis
  • diabetes mellitus
  • malignancy
  • pressure ulcers etc
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14
Q

Describe the management plan for venous ulcers. (10)

A
  • compression bandaging - to reduce venous stasis
  • debridement and cleaning
  • skin graft if large / refractory ulcers
  • antibiotics if infected
  • topical steroids to help with surrounding dermatitis
  • pentoxifylline (peripheral vasodilator)
  • adequate nutrition
  • lifestyle modification - mobilise to encourage venous flow in legs
  • leg elevation - reduce BP in LL
  • varicose vein surgery - prevent recurrence if ulcer caused by obvious superficial varicosities and no deep vein incompetence
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15
Q

When is compression bandaging contraindicated in venous ulcers?

A

In arterial disease, hence do ABPI beforehand to rule out arterial insufficiency (i.e. if ABPI<0.8 do not use compression bandaging)

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16
Q

When is referral considered for venous ulcers?

A
  • diagnostic uncertainty
  • ulcer rapidly deteriorating or has an atypical location/appearance
  • arterial or mixed venous/arterial disease
  • DM, RA or systemic vasculitis, malignancy
  • poor ankle mobility
  • suspected iliac vein stenosis
17
Q

What are some complications of venous ulcers? (2)

A
  • recurrence (below-knee graduated compression stockings help)
  • infection
18
Q

Describe the prognosis of venous ulcers.

A

Good - results are better if patients are mobile with few comorbidities