Cardiac arrest (A&E) Flashcards

1
Q

Define cardiac arrest.

A

Sudden state of circulatory failure due to loss of cardiac systolic function

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2
Q

Which four specific cardiac rhythm disturbances lead to cardiac arrest?

A
  • ventricular fibrillation (VF): shockable rhythm
  • pulseless ventricular tachycardia (VT): shockable rhythm; absence of carotid pulse in the presence of sinus tachycardia
  • pulseless electrical activity (PEA): non-shockable rhythm; absence of carotid pulse in the presence of sinus rhythm
  • asystole: non-shockable rhythm
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3
Q

What are the most common causes of ventricular tachycardia and fibrillation? (2)

A

IHD and acute MI

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4
Q

What is Torsades de pointes (cardiac arrest)?

A

Subgroup of polymorphic VT in patients with underlying prolonged QT interval, sometimes related to hypomagnesaemia

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5
Q

List the reversible causes of cardiac arrest. (4+4)

A

4 H’s:

  • Hypoxia - give O2
  • Hypothermia
  • Hyperkalaemia/Hypokalaemia
  • Hypovolaemia - IV fluids

4 T’s:

  • Thrombosis
  • Tension pneumothorax - may cause PEA (pulseless electrical activity)
  • Tamponade - especially in Trauma
  • Toxins
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6
Q

What are the most common underlying causes of cardiac arrest? (3)

A
  • ischaemic heart disease
  • MI
  • in some cases: respiratory arrest triggered by opioid toxicity
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7
Q

What are the clinical features of cardiac arrest? (5)

A
  • symptoms preceded by fatigue, fainting, blackout, dizziness
  • patient unresponsive and unconscious
  • not breathing
  • absence of circulation - no carotid pulses
  • cardiac rhythm disturbance
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8
Q

What are some risk factors for cardiac arrest? (9)

A
  • coronary artery disease (CAD)
  • LV dysfunction
  • age
  • hypertrophic cardiomyopathy (HCM)
  • arrhythmogenic RV dysplasia (ARVD)
  • long QT syndrome (LQTS)
  • medications prolonging QT/causing electrolyte disturbances
  • acute medical or surgical emergency
  • poisoning/illicit substances (opioids)
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9
Q

What are the first-line investigations for cardiac arrest? (3)

A
  • continuous cardiac monitoring
  • bloods - FBC, serum electrolytes, ABG, cardiac biomarkers
  • point of care ultrasound (POCUS)
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10
Q

Why is continuous cardiac monitoring important in cardiac arrest?

A

To identify if the rhythm is shockable or non-shockable

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11
Q

List shockable rhythms in cardiac arrest. (2)

A
  • pulseless VT
  • VF
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12
Q

List non-shockable rhythms in cardiac arrest. (2)

A
  • PEA (pulseless electrical activity)
  • asystole
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13
Q

When should you do ECG in cardiac arrest?

A

Immediately after return of spontaneous circulation

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14
Q

What might ECG show in cardiac arrest?

A

Monomorphic VT

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15
Q

Why would you do FBC in cardiac arrest?

A

Cardiac arrest may be due to hypovolaemia –> low Hct

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16
Q

Why would you do serum electrolytes in cardiac arrest?

A

Arrest may be due to electrolyte abnormalities, especially hyperkalaemia and hypokalaemia

17
Q

Describe the American College of Cardiology/American Heart Association/Heart Rhythm Society classification of ventricular arrhythmias (cardiac arrest). (5)

A
  • VT: 3+ consecutive complexes originating in the ventricles at >100bpm
    • sustained VT lasts >30s or results in haemodynamic compromise
  • monomorphic VT: VT with a stable single QRS morphology from beat to beat
  • polymorphic VT: VT with a changing QRS morphology from beat to beat
  • Torsades de pointes: polymorphic VT in setting of a prolonged QT interval, with waxing and waning of QRS amplitude
  • VF: rapid, grossly irregular electrical activity with marked variability in waveform; ventricular rate usually >300bpm (cycle length <200ms)
18
Q

What are the two shockable rhythms in cardiac arrest?

A
  • pulseless VT
  • VF
19
Q

What is the management for an unwitnessed event of cardiac arrest with a shockable rhythm (VT/VF)?

A
  1. defibrillate (shock)
  2. CPR for 2 mins, then assess rhythm (shock again if still VT/VF)
  3. IV adrenaline 1mg after 3rd shock, and then every 3-5min
  4. if persisting after 3rd shock, give IV amiodarone 300mg (or lidocaine)
  5. a further dose of amiodarone 150mg should be given if VT/VF after 5 shocks
20
Q

How does the management of shockable cardiac arrest change if it was a witnessed attack in a monitored patient?

A

Administer up to 3 quick successive (stacked) shocks, rather than 1 shock followed by CPR (like in unwitnessed event)

21
Q

What if IV access cannot be achieved in cardiac arrest (e.g. for adrenaline/amiodarone)?

A

The drugs should be given via the intraosseous (IO) access in the proximal tibia

22
Q

What can be given for cardiac arrest if Torsades de pointes is the cause?

A

Magnesium sulfate

23
Q

What are the two non-shockable rhythms in cardiac arrest?

A
  • PEA (pulseless electrical activity)
  • asystole
24
Q

What is the management for non-shockable cardiac arrest?

A
  1. CPR for 2 mins, then reassess
  2. IV adrenaline 1mg ASAP (after first cycle), then every 3-5 mins
25
When are thrombolytic drugs given for cardiac arrest?
- should be considered if a PE suspected - if given, CPR should be continued for an extended period of 60-90 mins
26
What do we need to optimise after successful resuscitation in cardiac arrest?
O2 sats of 94-98% (give oxygen)
27
Summarise the treatment flowchart for cardiac arrest (advanced life support).
- CPR 30:2 + attach defibrillator/monitor - assess rhythm - shockable: 1 shock --> immediately resume CPR 2 mins - non-shockable: immediately resume CPR 2 mins - reassess rhythm - (shockable: after 3 shocks, give 1mg adrenaline IV every 3-5min + 300mg amiodarone IV)
28
What is post-cardiac arrest treatment? (5)
- ABCDE approach - controlled oxygenation and ventilation (target 94-98% and normal PaCO2) - 12-lead ECG - temperature control/therapeutic hypothermia - treat precipitating / reversible causes
29
How can we treat the underlying causes of cardiac arrest post-attack? (8)
- Hypoxia - oxygen - Hypothermia - warm slowly - Hypokalaemia/Hyperkalaemia - correction of electrolyte levels - Hypovolaemia - IV colloids, crystalloids and blood products - Thrombosis - treat as PE/MI (thrombolytics and extend CPR by 60-90min) - Tension pneumothorax - aspiration or chest drain - Tamponade - pericardiocentesis - Toxins - antidote for toxin
30
What are some complications of cardiac arrest? (5)
- irreversible hypoxic brain damage - rib and sternal fractures - ischaemic liver injury - renal acute tubular necrosis - death
31
Describe the prognosis of sudden cardiac arrest.
Generally poor, and those who survive may have complications of many organ systems due to ischaemic injury
32
What can improve the survival rate of sudden cardiac arrest outside of the hospital?
Early provision of CPR, including compression-only CPR by bystanders