Epistaxis (ENT) Flashcards

1
Q

Define epistaxis.

A

Nosebleed - bleeding from the nostril, nasal cavity and/or nasopharynx

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2
Q

What is the most common site of bleeding in epistaxis?

A

95% arise at Little’s area of the anterior septum - Kiesselbach plexus (where vessels supplying nasal mucosa anastomose with each other)

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3
Q

Who is epistaxis most common in?

A

Children and older people

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4
Q

How can epistaxis be classified? (2)

A
  • anterior epistaxis (90%) - blood flowing out of one nostril, mostly originating from Kiesselbach plexus
  • posterior epistaxis (rare) - blood running down throat, high risk of aspiration and airway compromise, both nostrils, originates from Woodruff plexus (vascular network in lateral wall)
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5
Q

What are the clinical features of epistaxis? (4)

A
  • blood in one nostril or both
  • bleeding starting at the nostrils (anterior epistaxis if blood not in throat)
  • septal deviation - increased likelihood of epistaxis
  • elevated BP
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6
Q

What are the risk factors for epistaxis?

A
  • dry weather / humidity
  • allergies
  • minor nasal trauma (nose picking/rubbing)
  • primary coagulopathy (haemophilia, VWD)
  • anatomical irregularities - deviated septum
  • hyperaemia
  • hypertension
  • inflammation
  • familial hereditary haemorrhagic telangiectasia
  • granulomatosis with polyangiitis
  • thrombocytopenia - ITP, TTP
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7
Q

What is familial hereditary haemorrhagic telangiectasia (risk factor for epistaxis)?

A
  • autosomal dominant condition
  • characterised by multiple telangiectasia (small dilated broken blood vessels) over skin and mucous membranes
  • causes spontaneous, recurrent nosebleeds
  • first-degree relatives will also have it
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8
Q

What are the features of granulomatosis with polyangiitis (risk factor for epistaxis)? (6)

A
  • epistaxis
  • sinusitis
  • dyspnoea
  • saddle-shaped nose
  • rapidly progressive glomerulonephritis
  • cANCA positive
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9
Q

What is the difference between idiopathic thrombocytopenia purpura (ITP) and thrombotic thrombocytopenia purpura (TTP)?

A
  • ITP - isolated thrombocytopenia in a well person, also causes petechiae and purpura, treatment with oral prednisolone
  • TTP - isolated thrombocytopenia in an unwell person: HUS (haemolytic anaemia, thrombocytopenia, AKI), fever, neurological signs
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10
Q

How is epistaxis diagnosed?

A

Clinical diagnosis - bleeding from nose or back of throat

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11
Q

When do you do FBC & group and save for epistaxis? (5)

A

If haemodynamically unstable, significant blood loss, frail and elderly, bleeding tendency, on anticoagulation

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12
Q

What form of imaging might we do for epistaxis?

A

CT paranasal sinuses - may demonstrate fracture, neoplasm, polyposis

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13
Q

What are some differential diagnoses for epistaxis? (2)

A
  • haemoptysis - respiratory signs (cough, dyspnoea, wheeze, abnormal breath sounds)
  • haematemesis - GI symptoms (abdominal pain, melaena, Hx PUD)
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14
Q

How do we manage epistaxis if haemodynamically unstable (>110bpm and/or SBP<90mmHg)?

A
  • ABC approach
  • begin fluid resuscitation
  • may need blood, FFP, platelet transfusion and fibrinogen supplementation
  • consider vasoconstrictor +/- local anaesthetic spray, safeguarding in children, supportive care, admission, analgesia
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15
Q

How do we manage epistaxis if haemodynamically stable?

A
  • nasal first aid - pinch cartilaginous (soft) area of nose firmly and bend head forward (NOT BACK as blood may enter pharynx and cause haematemesis)
  • if this does not work (after 10-15min): then cautery, then nasal packing
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16
Q

What is 1st, 2nd and 3rd line for persistent epistaxis despite initial measures?

A
  • 1st line - electrocautery or chemical cautery (silver nitrate)
  • 2nd line - anterior nasal packing + analgesia + supportive care +/- admission
  • 3rd line - ENT referral for posterior packing + analgesia
  • may require sphenopalatine ligation in theatre
17
Q

What do we do after epistaxis resolved?

A

Topical intranasal antibiotic cream (e.g. mupirocin, chlorhexidine/neomycin) or petroleum jelly + nasal hygiene education + (cautery of bleeding points after packing removed)

18
Q

What is 1st-line treatment for recurrent epistaxis?

A

ENT specialist referral (+ Naseptin - antiseptic cream)

19
Q

What do we do if a patient has posterior epistaxis?

A

Refer to ENT specialist

20
Q

What are some complications of epistaxis? (8)

A
  • acute bacterial rhinosinusitis (spontaneously heals after removing packing/short course Abx)
  • aspiration pneumonia
  • recurrent epistaxis
  • cardiovascular compromise
  • septal perforation due to bilateral cautery
  • toxic shock syndrome (from nasal packing - treat by removal of packing and Abx)
  • hypoxia
  • CVA associated with interventional embolisation
21
Q

Describe the prognosis of epistaxis.

A

Most patients respond to treatment, particularly to nasal packing