Vasoregulation Flashcards
1
Q
Name some vasoregulating drugs:
A
Nitroglycerin,
Alpha1 antagonist: prazosine, doxasozine
Hydralazin
2
Q
What’s the mechanism of nitroglycerin?
A
Ca2+ channel blockers
3
Q
What’s the mechanism of hydralazin
A
PDE- inhibitors
RAA system blockers
4
Q
Pharmacological effects of vasoregulators:
A
- Arterial vasodilation peripherial resistance, afterload decreases
- Venodilation CVP decreases preload will decrease
- Water excretion preload will decrease
- Does not alter contractility BUT heart performance increases!! + decrease blood pressure.
5
Q
Indications og vasoregulating drugs
A
- Heart failure
- Hypertension
- Proteinuria
6
Q
Side effects of vasoregulating drugs:
A
- Azotaemia
- Hypotension tiredness, faintness
- GI-disturbances: anorexia, vomiting, diarrhea