Parasympatholytic Flashcards

1
Q

what kind of drugs are here?

A

Anticholinergic, muscarinic receptor antagonist

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2
Q

Name one drug that is a parasympatholytic?

A

Atropine

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3
Q

What active substances are parasympatholytic?

A

Atropine, glycopyrrolate, homatropine, tropicamide, Ipratropium, Benzethimid, Butyl-scopalamine

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4
Q

Atropine,

A

Eye (cyclopegia, mydresis. Cardiovascular system. GI-tract - hyposalivation. Bronchi - bronchidilation, decrease mucous secretion.

  • highly toxic, crosses BBB
  • Clinical: premedication, OP-toxicosis, uveitis
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5
Q

glycopyrrolate

A

indication: preanesthetic anticholinergic agent in dogs and cats.
In dogs it reduces salivary, tracheobronchial and pharyngeal secretions, reduces free acidity of gastric secretion, and blocks cardiac vagal inhibitory reflexes.

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6
Q

homatropine,

A

diagnostics in eye exam

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7
Q

tropicamide,

A

diagnostics in eye exam

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8
Q

Ipratropium,

A

COPD (Chronic obstructive pulmonary disease) and asthma (inhalation)
- very low BBB penetration , so very safe

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9
Q

Benzethimic

A

antidiarrheal

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10
Q

Butyl-scopalamine.

A

anti-spasmatic, colic

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11
Q

Explain the effect of antidiarhoels and one example:

A

Segments inhibition are inhibited ,

Benzethimide: decreases secretion and motility

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12
Q

Explain the effect of antidiarhoels and one example:

A

Segments inhibition are inhibited ,

Benzethimide: decreases secretion and motility

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13
Q

Mydriatic used for treatment of uveitis

A

Atropine

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