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Pharma mt2 > JAK-inhibitors > Flashcards

JAK-inhibitors Flashcards

1
Q

Name the JAK inhibitors

A

Oclacitinib

Lokivetmab

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2
Q

Indications of JAK-inhibitors

A

Rheumatoid arthritis
Crohn disease
Leukemias
Alopecia

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3
Q

Pharmacological effects of Oclacitinib:

A
  • Antiflammatory
  • Antiallergic
  • Antipruritus
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4
Q

Pharmacokinetic of Oclacitnib:

A
  • Excellent per os absorption
  • food
  • Metabolism:liver
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5
Q

Side-effects of Oclacitnib:

A

HAEMATOLOGY and BIOCHEMISTRY

  • NEU, EO, MONO, TC! Decreased.
  • cholesterol increased.
  • Liver, kidney Ø
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6
Q

Indication of Lokivetmab

A

Itching

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Pharma mt2 (13 decks)

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