Vasculitis Flashcards
1
Q
what is it?
A
inflammation of blood vessels
2
Q
example
A
churg-strauss syndrome
3
Q
what is churg-strauss syndrome?
A
eosinophilic granulomatosis with polyangiitis
4
Q
presentation of churg-strauss syndrome
A
epistaxis inflamed lungs haematuria varied presentation purpuric rash peripheral neuropathy pericarditis myocarditis glomerulonephritis
5
Q
what causes the symptoms of churg-strauss syndrome
A
abnormal accumulation of large number of antibodies
increased eosinophils
causing inflammatory and allergic response
directly causing inflammation of veins and small and medium-sized arteries
6
Q
clinical features
A
epistaxis haematuria fatigue widespread wheeze raised RR and HR purpuric rash - non-blanching
7
Q
investigations
A
FBC CXR ECG CRP bloods U&Es VBG p-ANCA antibodies
8
Q
how to manage asthma acutely?
A
oxygen salbutamol hydrocortisone ipratropium bromide prednisolone consider magnesium sulphate if tiring and signs of life-threatening asthma contact ITU
9
Q
blood results
A
raised CRP
low Hb
raised eosinophils
10
Q
CXR results
A
patchy opacification of both lungs - inflammation
11
Q
management
A
treat presentation
steroids
