Vasculitides

Question 1

Define Vasculitides

Answer 1

small vessel vasculitis
Mainly ANCA  (anti nutreophyle, cytoplasmic AB)
associates vasculitis (3 forms-microscopic polyangitis, Granumalotis with polyangitis and Eosinophillic granulamotis with polyangitis)

and Immune complex vasculitides- (IGA disease)

Question 2

Signs and Sx of Vasculitides

Answer 2

generally-fever, malaise, fatigue, etc
mainly be aware of them-if can’t think infection, and can’t find malignancy—> then maybe its vasculitis

ANCA-GPA-upper airway-nose bleed, sinusitis, saddle nose
Pulm involvement,
Glomerulonephritis

IGa disease-deposit in vessels-skin, joints,
purpuric rashes, bowel inflammation, arthritis, abdominal pain
usually follows an upper airway disease

Question 3

Aetiology and risk factors of Vasculitides

Answer 3

ANCA-damage to neutrophils cause reaction-inflammation around the area that the neutrophils are damaged in

Question 4

Investigation of Vasculitides

Answer 4

ANCA present-

Or High IgA

Question 5

Epiemology of Vasculitides

Answer 5

rare af-but important to have as differential for fevers if no infection or malignancy found