Vasculature of CNS Flashcards
two routes to get blood to cranial vault
internal carotid arteries 2x left and right
vertebral arteries 2x left and right
internal carotid system
enter skull at carotid canal
join cerebral arterial circle
branches of cerebral arterial circle
three cortical branches
off of these three - deep perforating branches
branches of internal carotid
middle cerebral a.
posterior communicating a.
anterior cerebral a.
lenticulostriate arteries
deep penetrating arteries
lentiform and striatum nuclei (basal nuclei)
branches of middle cerebral arteries
anterior cerebral artery
runs in longitundinal fissure and above corpus callosum
left and right 2x
corpus callosum
connects L and R cerebral hemispheres
vertebral arteries
enter cranium vault via foramen magnum
-meet as basilar artery
basilar artery
where vertebral arteries come together
branches of basilar artery
posterior cerebral arteries
posterior inferior cerebellar artery
first large branch off of vertebral arteries
-serves posterior / inferior cerebellum
anterior inferior cerebellar artery
second large branch off of vertebral arteries
superior cerebellar artery
branch off of basilar artery
pontine arteries
branches of basilar artery
-blood to pons
posterior spinal artery
arises off of vertebral artery or posterior inferior cerebellar artery
anterior spinal artery
single artery that arises from both vertebral arteries
blood brain barrier
physiologic barrier between intravascular space and CNS ECF
in brain and spinal cord
two major types of capillaries
continuous and fenestrated
continuous capillaries
in CNS
no pores or fenestrations
tight junctions between endothelial cells
endothelial cells lining capillaries that form blood brain barrier
components of blood brain barrier
capillary lined by endothelial cells (continuous)
-tight junctions between them
astrocyte end feet
-do NOT form blood brain barrier