varicella Flashcards
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highest risk of Fetal varicella syndrome (FVS) lowest when ?
before 20 weeks gestation
Management of chickenpox exposure in pregnancy, i.e. post-exposure prophylaxis (PEP) ?
If a woman is exposed to chickenpox during pregnancy, a history should be taken of whether she previously had chickenpox or varicella vaccination. If she has, no further action is needed
If the woman is unsure about previous chickenpox or has never had chickenpox, a blood test for varicella zoster virus (VZV) antibodies should be performed.
For susceptible women (negative antibodies) exposed in the first 20 weeks of pregnancy?
varicella zoster immunoglobulin (VZIG) is recommended.
For susceptible women (negative antibodies) exposed from 20 weeks of pregnancy
either VZIG or ORAL aciclovir FROM DAYS 7 TO 14 AFTER EXPOSURE is recommended.
pregnant women with symptomatic chickenpox present within 24 hours of the onset of the rash and if they are 20+ weeks’ gestation
Oral aciclovir
if the woman is < 20 weeks the aciclovir should be ‘considered with caution’
if the pregnant woman <= 20 weeks gestation is not immune to varicella
should be given varicella-zoster immunoglobulin (VZIG) as soon as possible
