Leishmania Flashcards

1
Q

Leishmaniasis is caused by ?

A

intracellular protozoa Leishmania

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2
Q

forms of leishmaniasis ?

A

Cutaneous

mucocutaneous

visceral

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3
Q

Cutaneous leishmaniasis are caused by ?

A

Leishmania tropica or Leishmania mexicana

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4
Q

protozoa Leishmania, which are spread by

A

sandflies

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5
Q

clinical manifestation of Cutaneous leishmaniasis

A

crusted lesion at the site of bite

may be an underlying ulcer

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6
Q

Cutaneous leishmaniasis are diagnoses by

A

punch biopsy from the edge of the lesion allowing for both histology and culture

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7
Q

cutaneous leishmaniasis acquired in South or Central America merits

A

treatment due to the risk of mucocutaneous leishmaniasis

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8
Q

cutaneous leishmaniasis acquired in Africa or India mx ?

A

conservative

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9
Q

Mucocutaneous leishmaniasis are caused by ?

A

Leishmania braziliensis

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10
Q

Leishmania braziliensis involve

A

mucosae of nose, pharynx

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11
Q

Visceral leishmaniasis caused by

A

Leishmania donovani

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12
Q

Leishmania donovani occurs in which areas?

A

Mediterranean, Asia, South America, Africa

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13
Q

skin clinical manifestation of Leishmania donovani

A

grey skin - ‘kala-azar’ means black sickness

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14
Q

clinical manifestation of Leishmania donovani

A

fever, sweats, rigors
massive splenomegaly. hepatomegaly
weight loss

occasionally patients may report increased appetite with paradoxical weight loss

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15
Q

hypersplenism due to Leishmania donovani causes ?

A

pancytopaenia

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16
Q

gold standard for diagnosis of Leishmania donovani

A

bone marrow or splenic aspirate

17
Q

x

A
18
Q

x

A
19
Q

x

A
20
Q

x

A
21
Q

x

A
22
Q

x

A
23
Q

x

A
24
Q

Tx for Leishmaniasis

A

Miltefosine