Vancomycin Flashcards
1
Q
moa
A
inhibits cell wall synthesis
targets transglycosylation reaction
2
Q
pharmacokinetics
A
highly water soluble
poor oral absorption
3
Q
indication for oral vancomycin
A
pseudomembranous colitis
4
Q
resistance
A
modification of d-ala d-ala terminus
5
Q
adverse reaction when combined with aminoglycosides
A
ototoxicity
6
Q
adverse reaction when combined with NSAID
A
nephrotoxicity
7
Q
adverse reaction when combined with loop diuretics
A
ototoxicity
8
Q
caused by rapid vancomycin infusion causing increased histamine release
A
red man/ red neck syndrome
9
Q
indications
A
MRSA
acute bacterial endocarditis
meningitis
septicemia
10
Q
other drugs that targets cell wall or cell membrane
A
BacitFosCycloDap
bacitracin
Fosfomycin
cycloserine
daptomycin
