Valvular Disease - Causes Flashcards
4 cause classifications
rheumatic
congenital
ischaemic
infective
Infective
?/? endocarditis via direct infection can cause ?
valve infl has two consequences:
-short term - ? exposure and ? development
-long term ? impairment due to post-inflam ?
? sided valves are more freq the site - ? from valve thrombosis classically produces infarcts where?
bact fungal valvulitis collagen thrombus fx scarring left emboli systemic organs
most common cause of chronic heart valve scarring?
an ? mediated disorder occurring in ?, usually following ?/pharyngitis caused by ? ? ?
rheumatic fever immune children tonsilitis GAS
Rheum fever
Ab prod against ??? which cross react with cardiac ? - > self-limiting myocarditis/?
although its self limiting - damage to heart valves that heals by progressive ? of valve ? and ? ?
leads to ?, fibrotic valve leaflets, often with 2* ?
GAS antigens pericarditis fibrosis leaflets chordae tendinae shrunken calcification
Congenital
?? is commonly due to calcification of a congenital ? aortic valve
AS
bicuspid
Ischaemic
?? is often caused by ? muscle dysfunction post ?
MR
papillary
infarction
