Valsartan (ARB - Angiotensin II Receptor Blocker)

Question 1

Expected Pharmacological Action:

Answer 1

Blocks angiotensin II receptors, preventing vasoconstriction and aldosterone release → lowers BP

Question 2

Therapeutic Use:

Answer 2

Hypertension
Heart failure
Post-myocardial infarction (to reduce mortality)

Question 3

Complications:

Answer 3

Hypotension
Hyperkalemia
Dizziness
Angioedema (rare but possible)

Question 4

Contraindications/Precautions:

Answer 4

Pregnancy (Category D – fetal harm risk)
Renal artery stenosis
Severe kidney disease
Hypersensitive

Question 5

Interactions:

Answer 5

Potassium supplements & potassium-sparing diuretics → increase hyperkalemia risk
NSAIDs → decrease effectiveness
Lithium
ACE Inhibitors
Foods High in Potassium

Question 6

Client Education:

Answer 6

Monitor blood pressure and potassium levels
Avoid high-potassium foods
Use another form of Birth Control
Take as prescribed and @ same time everyday
Avoid NSAIDS

Question 7

Dosage:

Answer 7

Hypertension: 80–320 mg daily
Heart failure: 40–160 mg twice daily