Metoprolol (Beta-Blocker - Cardioselective)

Question 1

Expected Pharmacological Action:

Answer 1

Blocks beta-1 receptors in the heart, decreasing heart rate and blood pressure. Decrease release on renin and decrease of CO

Question 2

Therapeutic Use:

Answer 2

Hypertension
Angina
Heart failure
Myocardial infarction prevention

Question 3

Complications:

Answer 3

Bradycardia
Hypotension
Fatigue
Heart failure (if dosage is too high)
Photosensitive
Bronchospasm

Question 4

Contraindications/Precautions:

Answer 4

Bradycardia
Hypotension
Asthma (high doses may affect beta-2 receptors and cause bronchoconstriction)
Hypersensitive
Heart Blocks

Question 5

Interactions:

Answer 5

Digoxin → increases risk of bradycardia
Calcium channel blockers (e.g., verapamil, diltiazem) → excessive cardiac suppression
MAOI

Question 6

Client Education:

Answer 6

Do not stop abruptly (risk of rebound hypertension & angina)
Monitor heart rate before taking (hold if HR < 50 bpm)
Change positions slowly to prevent dizziness
Diabetics take blood sugar often

Question 7

Dosage:

Answer 7

25–100 mg