Valley Practice Examination Flashcards
A number that shows how much of a gas will dissolve in a liquid at some specified temperature.
Ostwald
A principle for calculating cardiac output from oxygen uptake or carbon dioxide elimination and oxygen or carbon dioxide concentrations in arterial and venous blood.
Fick principle
Described behavior of non-ideal gases.
van der Waal
Gas pressure is inversely proportional to gas volume at constant temperature.
Boyle
The total pressure of a mixture of gases is equal to the sum of the partial pressures.
Dalton
6.02 x 10^23
Avogadro
Gas pressure increases if temperature increases and volume does not change.
Gay-Lussac
One mole of ideal gas occupies 22.4 liters of 0’C and 1 atm.
Avogadro
Volume increases when temperature increases, if pressure is constant.
Charles
Twice as much O2 will dissolve in arterial blood if the alveolar partial pressure of O2 is doubled.
Henry
A number that reveals whether or not flow is laminar or turbulent.
Reynolds
Concentration effect.
Fick’s law of diffusion
Explained how pressure, tube radius, tube length, and fluid viscosity contribute to laminar flow.
Hagen-Poiseuille
Tension in the wall of a blood vessel is proportional to the radius
Laplace
The lateral pressure of fluid flowing through a constricted segment of tubing is decreased.
Bernoulli
What law or principle explains normal tidal breathing?
a. Boyle’s law
b. Hagen-Poiseuille’s law
c. Dalton’s law
d. Bernoulli’s principle
a. Boyle’s law
Muscle relaxants are:
a. esters
b. ethers
c. thiosulfates
d. quaternary ammonium bases
d. quaternary ammonium bases
Desflurane, enflurane, isoflurane and sevoflurane are halogenated:
a. amines
b. esters
c. amides
d. ethers
d. ethers
The equation for calculating systemic vascular resistance(SVR) is 80 x SVR = (MAP - CVP)/CO, where MAP is mean arterial pressure, CVP is central venous pressure, and CO is cardiac output. What law or principle permits this calculation?
a. LeChatelier’s principle
b. Ohm’s law
c. Superimposition principle
d. Low of Laplace
b. Ohm’s law
Consider a weak acid in solution when the pH = pKa for the weak acid. Which of the following statements is correct?
a. Only the nonionized form of the species exists
b. pH = 7.0
c. Only ionized form of the species exist
d. the concentration of ionized species is equal to the concentration of nonionized species
d. the concentration of ionized species is equal to the concentration of nonionized species
Which of the following is the salt form of a weak acid?
a. Drug sulfate
b. Drug hydrochloride
c. Sodium drug
d. Drug phosphate
c. Sodium drug
Which orally administered drug will be most nonionized and best absorbed across the stomach wall when stomach pH = 2.0?
a. A weak base with pKa = 4.5
b. A weak base with pKa = 8.6
c. A weak acid with pKa = 3.6
d. A weak acid with pKa = 6.2
d. A weak acid with pKa = 6.2
Which of the following drugs is most nonionized at body pH of 7.4?
a. A weak acid with pKa of 7.4
b. A weak base with pKa of 7.4
c. A weak acid with pKa of 5.0
d. A weak base with pKa of 5.0
d. A weak base with pKa of 5.0
A local anesthetic is:
a. weak base with pKa less than 7.4
b. weak base with pKa greater than 7.4
c. weak acid with pKa less than 7.4
d. weak acid with pKa greater than 7.4
b. weak base with pKa greater than 7.4
4-8 mesh soda lime
a. prevents channeling while providing an adequate surface area for CO2 absorption
b. provides high resistance to air flow
c. both a and b
d. neither a nor b
a. prevents channeling while providing an adequate surface area for CO2 absorption
What is the partial pressure of a gas if its concentration is 5%?
a. 5 mmHg
b. 25 mmHg
c. 38 mmHg
d. 125 mmHg
c. 38 mmHg
If a gas exerts a partial pressure of 15 mmHg, its concentration is(in percent):
a. 0.25%
b. 0.5%
c. 1.5%
d. 2.0%
d. 2.0%
In the reaction of CO2 with soda lime, the final products are
a. bicarbonates
b. carbonic acids
c. hydroxides
d. carbonates
d. carbonates
The law that relates the volume of gas released into the atmosphere from an O2 tank is:
a. Boyle’s law
b. Gay-Lussac’s law
c. Henry’s law
d. Charles’ law
a. Boyles law
Which pulmonary function test uses Boyle’s law?
a. Vital capacity
b. Plethysmography for determination of FRC
c. Respiratory exchange ratio
d. Nitrogen washout test for determination of FRC
b. Plethysmography for determination of FRC
The generation of colloid osmotic pressure in the plasma is the principle function of:
a. globulin
b. fibrinogen
c. sodium
d. albumin
d. albumin
A 3% stock solution of drug “X” is available. You need to make 50 mL of 0.6 mg/mL solution. How many mL will you take from stock solution to make the dilute solution?
a. 1 mL
b. 10 mL
c. 100 mL
d. 1000 mL
a. 1 mL
In the following graphs, the solid line shows the alveolar uptake of halothane when it is delivered to the patient in O2. What will happen to this uptake curve when halothane is delivered to the patient in 70% N20? The uptake will be:
a. faster(dashed line A)
b. slower(dashed line B)
c. unchanged(dashed line C)
a. faster(dashed line A)
Given 25 mL of 2% Xylocaine, how many mg of the drug are there?
a. 1000
b. 500
c. 250
d. 50
b. 500
Sevoflurane is added to a flask sitting on a table. What is the concentration of sevoflurane above the liquid?
a. 16%
b. 22%
c. 32%
d. 49%
b. 22%
Five mL of a 1:1000 concentration of epinephrine contains how many milligrams?
a. 0.5 mg
b. 1.0 mg
c. 5.0 mg
d. 50.0 mg
c. 5.0 mg
If the flow of oxygen from an E-size tank is 5 liters per minute, the tank will last:
a. 1 hour
b. 2 hours
c. 3 hours
d. 5 hours
b. 2 hours
The lipid bilayer of the cell membrane is most impermeable to which of the following substances?
a. Physostigmine
b. Potassium ions
c. Carbon dioxide
d. Desflurane
b. Potassium ions
If the agents below, which has the lowest blood/gas partition coefficient?
a. Enflurane
b. Halothane
c. Isoflurane
d. Desflurane
d. Desflurane
With a 6 liter per minute total flow and a mixture of 70% N20 and 30% O2, what is the flow of N20 per minute?
a. 3.0 liters
b. 4.2 liters
c. 5.0 liters
d. 3.6 liters
b. 4.2 liters
The relative humidity of alveolar gas is:
a. 50%
b. 21%
c. 47%
d. 100%
d. 100%
When the pressure gauge on a tank of N20 begins to fall rapidly, the
a. tank is empty
b. tank no longer contains N20 in a liquid form
c. gas pressure in the tank is zero mmHg
d. tank contains only liquid N20
b. tank no longer contains N20 in a liquid form
The rotameter flowmeter is an example of a:
a. variable pressure difference flowmeter
b. constant diameter orifice flowmeter
c. fixed orifice flowmeter
d. variable orifice flowmeter
d. variable orifice flowmeter
An agent with a blood:gas partition coefficient of 12.0 and an oil:gas partition coefficient of 0.5:
a. builds up rapidly and lacks potency
b. builds up rapidly and is highly potent
c. builds up slowly and lacks potency
d. builds up slowly and is highly potent
c. builds up slowly and lacks potency
Substances that most readily cross the placental or BBB:
a. are highly lipid soluble
b. have high molecular weights
c. are highly ionized
d. are highly protein bound
a. are highly lipid soluble
The agent with the lowest oil:gas partition coefficient on the list below is:
a. halothane
b. desflurane
c. enflurane
d. isoflurane
b. desflurane
Immediately after onset of 50% N20 administration, the volume of the stomach may:
a. decrease
b. increase
c. remain unchanged
d. first decrease and then increase
b. increase
If flow is laminar and the radius of a tube is tripled, the flow through the tube will increase
a. 3-fold
b. 16-fold
c. 64-fold
d. 81-fold
d. 81-fold
What can be measured with a Wright’s respirometer?
a. Carbon dioxide absorption
b. Tidal Volume
c. Oxygen uptake
d. Dead space
b. Tidal Volume
1:500,000 concentration is:
a. 0.02 mcg/ml
b. 0.2 mcg/ml
c. 2.0 mcg/ml
d. 20.0 mcg/ml
c. 2.0 mcg/mL
What property of helium makes it a useful agent?
a. Low density
b. Low viscosity
c. Low molecular weight
d. Low blood solubility
a. Low density
When halothane is added to a flask containing 100% O2, the new concentration of O2 will be:
a. 15%
b. 21%
c. 68%
d. 83%
c. 68%
The concentration leaving the enflurane vaporizer will not be different than the dial setting if which of the following agents is mistakenly placed in the vaporizer?
a. Halothane
b. Isoflurane
c. Sevoflurane
d. Desflurane
c. Sevoflurane
The cylinder of N20 cools after it is turned on. What explains this cooling?
a. Venturi principle
b. Joule-Thompson effect
c. Charles’ law
d. Fick’s law of diffusion
b. Joule-Thompson effect
Tension in the blood vessel wall will be lowest in the:
a. capillary
b. femoral artery
c. inferior vena cava
d. ascending aorta
a. capillary
During diastole, the tension in the left ventricular wall increases. What explains this?
a. Joule-Thompson effect
b. Starling’s law
c. Ohm’s law
d. Law of Laplace
d. Law of Laplace
When you put an endotracheal tube in an autoclave, the cuff expands. This is an application of:
a. ideal(universal) gas law
b. Boyle’s law
c. Ohm’s law
d. Charles’ law
d. Charles law
When the length of an IV needle is doubled, what happens to flow from the IV bag, and what law applies?
a. Flow is doubled and Fick’s law applies
b. Flow is halved and Fick’s law applies
c. Flow is doubled and Hagen-Poiseuille’s’s law applies
d. Flow is halved and Hagen-Poiseuille’s’s law applies
d. Flow is halved and Hagen-Poiseuille’s’s law applies
How much carbon dioxide is dissolved in arterial blood when PaCO2 is 70 mmHg?
a. 4.69 mL CO2/100mL blood
b. 0.42 mL CO2/100 mL blood
c. 1.21 mL C02/100 mL blood
d. 0.21 mL CO2/199 mL blood
a. 4.69 mL CO2/100 mL blood