Vagina Flashcards
1
Q
Adenosis
etiology
pathology
A
caused by diethylstilbestrol (DES)-estrogen agonist
causes persistence of columnar cells in upper 2/3 of vagina that is derived from mallarian duct
2
Q
Vagina embryology
A
upper 2/3: mallarian duct (columnar in fetus -> stratified squamous in adults)
lower 1/3: urogenital sinus (stratified squamous)
3
Q
Adenosis risk
A
increased risk of clear cell adenocarcinoma
4
Q
DES-exposed mothers have a slightly increased risk of
A
breast carcinoma
5
Q
Embryonal rhabodomyosarcoma
pathology
population
A
grape-like mass in vagina (or penis)
usually girls
6
Q
Embryonal rhabdomyosarcoma
defining cell
staining
A
rhabdomyoblast
desmin and myogenin +
7
Q
Presentation of vaginal embryonal rhabdomyocarcoma
A
vaginal or penile bleeding
PE shows grape like mass
