Endometrium Flashcards

1
Q

Asherman syndrome

A

aggressive D&C
scrapes away basal layer of endometrium
secondary amenorrhea

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2
Q

Anovulatory phase

hormonal causes

A

unopposed estrogen

no progesterone to start ovulation phase

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3
Q

Acute endometritis

etiology

A

retained products of conception

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4
Q

Chronic endometritis
etiologies
defining pathological feature

A

PID, IUD, TB
plasma cells are defining feature
*lymphocytes are always present in endometrium

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5
Q

Endometrial polyps are commonly due to

A

tamoxifen exposure
weak agonist in uterus
growth of polyps

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6
Q

Endometriosis is what

A

endometrial tissue (glands and stroma) found in non-endometrial locations

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7
Q

What is endometriosis of the myometrium called?

A

adenomyosis

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8
Q

Most common site of endometriosis

A

ovary

formation of chocolate cyst

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9
Q

Endometriosis of soft tissue

lesions

A

gun powder lesions

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10
Q

Endometriosis of fallopian tubes may cause

A

infertility 2˚ to endometrial scarring

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11
Q

Endometrial hyperplasia

etiology

A

hyperplasia of endometrial glands relative to stroma

2˚ to unopposed estrogen exposure

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12
Q

Endometrial hyperplasia

pre- or post-menopausal

A

post-menopausal

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13
Q

Classification of endometrial hyperplasia

A

simple or complex

± cellular atypia

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14
Q

Endometrial carcinoma

pathways

A

from endometrial carcinoma
-dependent on unopposed estrogen
sporadic
-due to de novo p53 mutations

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15
Q

Sporadic endometrial carcinoma

histology findings

A

psammoma body formation

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16
Q

Histology of endometrial carcinoma

from hyperplasia pathway

A

“endometriod” appearance

looks similar to normal endometrium

17
Q

Leiomyomas
etiology
progression/regression phases

A

estrogen exposure
progresses during pregnancy
regresses after menopause
*no risk of progression to leiomyosarcoma

18
Q

Etiology of leiomyosarcomas

A

NOT FROM LEIOMYOMAS

arise do novo in post menopausal women

19
Q

Gross differences between leiomyoma and leiomyosarcoma

A

leiomyoma: multiple, white whorled masses
leiomyosarcoma: usually solidtary, necrosis and hemorrhage