Ovarian Tumors Flashcards
Two types of surface epithelial tumors
serous and mucinous
both are usually cystic
BRCA1 mutations cause cancer types in these locations
breast carcinoma
ovarian: serous carcinoma, may also be in fallopian tube
Endometriod ovarian tumors
malginancy potential
associations
usually malignant
associated with endometriosis and endometrial cancer in the endometrium
*if you find endometrial ca in ovary, be sure to look in the endometrium
Brenner tumors
tissue type
bladder-type tissue
Ovarian tumors like to metastasize to where
peritoneum
Tumor marker for epithelial ovarian tumors
CA-125
Struma ovarii
teratoma
composed of primarily thyroid tissue
Immature tissue in teratomas is usually of what type
neural ectoderm
Most common somatic malignancy in teratomas
squamous cell carcinoma
Dysgerminoma is analogous to what male tumor
seminoma
Dysgerminoma
histology
large cells w/ clear cytoplasm
Endometrial sinus tumor
mimics what
mimics yolk sac
Endometrial sinus tumor origin population histology tumor marker
yolk sac
young women/girls
glomeruloid appearance w/ Schiller-Duval bodies
AFP (alpha feta-protein) is tumor marker
Choriocarcinoma
mimics
tumor marker
agressiveness
mimics placenta
hCG is tumor marker
very aggressive, placenta looks for blood vessels
*very early hematogenous spread with multiple mets
Embryonal carcinoma
large primitive cells
early mets
