Ovary Flashcards
Hormone levels in polycystic ovarian syndrome
high LH to FSH
LH:FSH > 2
These hormones act on which cells/which actions
LH
FSH
estradiol
LH: theca cells to release androgens
FSH: granulosa cells to convert androgens -> estradiol
estradiol: induces LH surge
Residual ovarian follicle ie corpus leuteum secretes what
progesterone
functions to drive secretory phase and prepare endometrium for possible pregnancy
Non-pathological ovarian cysts result from what phenomenon
degeneration of follicles
occasionally forms cysts that are insignificant
How does a high LH: FSH ratio cause multiple cysts to be created
low levels of FSH cause degeneration of the follicle
form may cysts
High LH in PCOD causes
theca cells to secrete excess androgen
hirtuism –> excess hair in male distribution
Low FSH in PCOD causes
degenrations of follicles (not stimulated)
formation of ovarian cysts as a result
Fate of androgens in PCOS
converted to estrone in adipose tissue
increases risk for endometrial carcinoma
due to high levels of estrogen
Sx of PCOS
hirsutism, infertility, oligomenorrhea
insulin resistance possible –> T2D