Vaccinology

Question 1

Inactivated/killed vaccines produce ___ & ___ immune responses

Answer 1

Weaker & shorter duration

Question 2

In the absence of MDA, initial dosing of inactivated/killed vaccines entails

Answer 2

2 doses, 3-4 weeks apart

Question 3

With inactivated vaccines, effective immunity may not develop until

Answer 3

2-3 weeks after last dose

Question 4

With recombinant rabies vaccine, protective immunity is expected to develop by ___

Answer 4

28 days

Question 5

With recombinant FeLV, protective immunity expected within ___ of ___

Answer 5

7-10 days of 2nd dose

Question 6

Canarypox-vectored recombinant vaccines are

Answer 6

Non-adjuvanted

Question 7

In modified live vaccines, adjuvant is

Answer 7

Not required

Question 8

Types of recombinant vaccines (which is the only 1 available in N America?)

Answer 8

Subunit, deletion mutant, vectored, DNA (vectored)

Question 9

Modified live vaccine routes of admin

Answer 9

Parenteral (SC, IM), Mucosal (intranasal)

Question 10

Some recombinant vaccines contain

Answer 10

Adjuvant

Question 11

Partial immunity after ____ vaccines can occur within ___

Answer 11

Attenuated/modified live; hours

Question 12

Live vaccine ____ that are ___ can ____

Answer 12

Organisms; shed; immunize other animals in the population

Question 13

3-2-1 rule

Answer 13

Bx if persists > 3 mos post-vax, is > 2 cm diameter, size increase 1 mo post-vax

Question 14

FIP vaccination is not recommended because __

Answer 14

It is labeled for administration at > 16 weeks and kittens are often infected before then
It contains sereotype II, when sereotype I predominates