Clin Path + Labs

Question 1

Clotting of blood in test tubes can be prevented by the addition of ___, which ____

Answer 1

Sodium citrate or ethylenediaminetetracetic acid (EDTA), which cholate (bind) Ca2+, which is required (along with platelet phospholipids) for clotting, thereby inhibiting clotting

Question 2

__ activates antithrombin III, and is given during procedures to ___

Answer 2

Heparin; prevent clotting

Question 3

Coumarin drugs, ___, prevent clotting by __

Answer 3

Dicoumarin & warfarin; inhibiting activation of vitamin K

Question 4

Left shift is (definition)

Answer 4

An increased concentration of non segmented neutrophils (usually bands); when there is great demand for neutrophils in the tissues, younger stages (metamyelocytes, myelocytes, and rarely progranulocytes) may be present

Question 5

Left shift often occurs in response to

Answer 5

Relatively intense, often acute, inflammatory stimuli; left shift is often the hallmark of acute inflammation

Question 6

A regenerative left shift is characterized by a

Answer 6

leukocytosis due to neutrophilia and with immature neutrophils in the peripheral blood

Question 7

In a degenerative left shift, ___ (definition)

Answer 7

Total leukocyte count remains within normal range or only slightly elevated, but the occurrence of circulating young granulocytes is prominent