vaccines Flashcards
risk factors for cats
- Access to the outdoors
- Multi-cat households
- Indirect or direct exposure
- Age/Health of household members
- Immunosuppressive diseases
what diseases are covered in the feline 3 way vaccine?
Distemper (panleukopenia), Rhinotracheitis, Calici
what diseases are covered in the feline 4 way vaccine?
Distemper (panleukopenia), Rhinotracheitis, Calici + Chlamydia
what diseases are covered in the feline 5 way vaccine
Distemper (panleukopenia), Rhinotracheitis, Calici + Chlamydia + FeLV
what diseases are not included in the 5 way feline vaccine?
rabies, FIV, FIP
what is another name for Feline Panleukopenia
Distemper
what virus is associated with Feline Panleukopenia
parvovirus
what kills Feline Panleukopenia
Bleach, special disinfectants required to kill (virucidals)
what cats are most susceptible to Feline Panleukopenia
Kittens 3-5 months of age and unvaccinated cats
how is Feline Panleukopenia spread?
Direct:
○ Shed in all body secretions - urine, feces, ocular, nasal
○ Shed up to 6 weeks in urine and feces
Indirect:
○ Fomites (clothing, cages, dishes, etc)
○ Vectors (flies most likely)
○ Transplacental infection
Kittens infected through queen during pregnancy - causes permanent neurological problems or blindness
what are the clinical signs of feline panleukopenia
○ Develop in young unvaccinated cats
○ Fever 40-41.6℃
○ Depression, anorexia, vomiting +/- diarrhea
○ Ataxia
○ Can progress to coma, hypothermia and death
treatment for feline panleukopenia
○ Supportive
○ Fluids
○ Antiemetics
○ Antibiotics for secondary bacterial infection
○ Soft, smelly food
what are the 3 components of feline upper respiratory disease
● Feline herpesvirus (rhinotracheitis)
● Feline calicivirus
● Chlamydia
what percentage of feline upper respiratory disease cases are caused by herpesvirus & calicivirus
90
what is Feline Viral Rhinotracheitis called
Feline Herpesvirus
what are the symptoms of Feline Herpesvirus
● Attacks mucosa of upper airways and conjunctiva
● Causes necrosis of nasal turbinates
● Asymptomatic carriers: spread infection with no signs of disease
○ Often show c/s when stressed
● Easy to kill - inactivated in 24 hours
● Kittens most susceptible; can be infected by queen
what are the clinical signs of feline Viral Rhinotracheitis
○ Sneezing
○ Ocular discharge
○ Fever
○ Anorexia
○ Depression
what are the symptoms of Feline Calicivirus
Causes ulceration of tongue and palate
● Minimal effects on conjunctiva and upper airway
● Can cause viral pneumonia
● Carriers exist
● Painful and affected cats will not eat
what are the clinical signs of Feline Calicivirus
○ Moderate - mild nasal and ocular discharge
○ Oral Ulcers
○ Pneumonia
○ Joint Pain
○ Carriers will shed virus for years!
what are the symptoms of chlamydia
● Fragile bacteria
● Conjunctivitis
● Mild rhinitis
● Mucopurulent discharge
● ZOONOTIC: Bacteria may cause conjunctivitis in humans
how is feline upper respiratory disease complex spread
aerosols, direct contact, fomites
is there a cure for feline upper respiratory disease complex
no, only supportive care
how is FeLV spread
● Shed in all secretions
○ Urine, feces, nasal/ ocular discharge
● Spread transplacentally
● Spread through mutual grooming, sharing food bowls and litter boxes.
● Usually prolonged or repeated contact necessary
what are the 3 scenarios for FeLV infection
● Adequate immune system (Abortive Infections)
○ Virus is cleared
○ No c/s develop
○ Immunity develops
● Chronic infection (Progressive Infections)
○ Cat remains viremic (virus in blood)
○ Sheds virus
○ Often will develop c/s
● Latent Carrier State (Regressive Infections)
○ Virus remains in bone marrow
○ Reactivated with stress
clinical signs of FeLV
● Can affect cat’s body in many ways …
● No signs at all
● Progressive weight loss
● Poor coat condition
● Enlarged lymph nodes
● Fever
● Recurrent infections (skin, ear, respiratory)
● Often a cause of cancer and various blood disorders
how to diagnose FeLV
● ELISA test
○ blood test that can be done ‘in-house’
● IFA test
○ blood test sent to diagnostic lab
○ Usually sent out after + ELISA to confirm
treatment, prevention of FeLV
● NO CURE!
○ Most infected cats eventually die of FeLV related diseases, but can
have a quality of life
● Managing FeLV + cats involves treating specific problems
○ Secondary bacterial infections - anitbiotics
○ Severe anemia - blood transfussion
○ Proper veterinary recommended diet (NO RAW!)
● Prevent exposure to FeLV + cats
● Vaccinate
what is Feline Immunodeficiency Virus similar to in Humans
AIDS
what does FIV cause?
Causes suppression of the immune system (similar to HIV in
humans)
How is FIV spread
● Spread through saliva from bite wounds
○ Outdoor cats at highest risk
How long can cats live with FIV?
Cats can live 5-7 years with treatment
clinical signs of FIV
● Acute
○ Enlarged lymph nodes
○ Fever
○ Leukopenia
○ Turns into asymptomatic stage (can last for years)
● Chronic
○ Persistent diarrhea
○ Upper respiratory infections
○ Ocular and oral lesions
○ Gingivitis
○ Neurological signs - behavioral, twitches, seizures
how to diagnose FIV
● Clinical signs
● ELISA
○ Snap test with blood sample (in-house)
● IFA
○ Blood sent to diagnostic lab
● All tests dependent on cat mounting immune response as they detect antibodies in the blood …
○ If cat has not mounted response - false negative
○ If cat has been vaccinated - false positive
prevention/ treatment of FIV
● No cure!
● Prevent exposure to virus - cat bites
● Vaccine available (non-core)
● Treatment is supportive
● Cats can live normal lives if managed appropriately
○ Regular veterinary exams
○ Proper nutrition
○ Reduce exposure to infectious agents
What is FIP
Feline Infectious Peritonitis
how is FIP spread
●Most commonly infects kittens and cats < 1 year old.
○ Often those in crowded, shelter-like conditions
●Most commonly spread through fecal-oral route
○ Virus is shed in feces and oronasal secretions
● Contaminated fomites may play a role in transmission
○ inhalation
what are the clinical signs of FIP
Effective Immune System:
○ Recovers in primary phase of infection
○ No clinical signs
Ineffective Immune System:
○ Wet form
○ Dry form
○ Both are fatal
what are the symptoms of wet FIP
● Fluid accumulates in body cavities - enlarged/ distended abdomen
● Fever
● Dyspnea due to fluid on chest
● Weight loss
● Lethargic
● Anorexic
what are the symptoms of dry FIP
● Fever, lethargy, anorexia
● Weight loss
● Mesenteric lymph nodes palpable (enlarged)
● Ocular hemorrhage or lesions
● Icterus - if liver is affected
● Neurological signs
how to diagnose FIP
● Clinical signs
● Peritoneal/pleural analysis
● ELISA and IFA
○ These are not very reliable as they only indicate the cat has been exposed to the coronavirus, but not necessarily one that causes FIP
● Biopsy and necropsy exams
prevention and treatment of FIP
● Avoid overcrowding
● Keep litter boxes and kennels clean
● Intranasal vaccine … not reliable …
● Proper nutrition
● This disease is often secondary to FeLV
● No cure, fatal disease.
what are the 6 Risk Factors for Disease in Canines
○ Age
○ Contact with other dogs
○ Regional variations
○ Breed
○ Environmental exposure
○ Immunosuppressed
what are the canine infectious diseases
○ Canine Distemper virus
○ Canine Parvovirus
○ Canine Infectious Tracheobronchitis
○ Canine Infectious Hepatitis
○ Canine Coronavirus
○ Leptospirosis
○ Lyme Disease
○ Rabies
how is canine distemper spread
Spread by aerosols and through placenta
○ Virus particles in the air, puppies during pregnancy
what species does distemper affect
○ Fox, coyotes, wolves, ferrets, racoon, badger
what does canine distemper affect
● Affects all body systems
○ Fever, vomiting, diarrhea, coughing, seizures
○ Ocular & nasal discharge, hard pad disease
is there treatment for canine distemper
no, only supportive
what does distemper cause
● Animals that do survive often have severe neurological
problems
○ Seizures
● Damaged tooth enamel
● High morbidity rate
○ unvaccinated animals very likely to get sick
● High mortality rate
○ infected animals will likely die