antimicrobial Flashcards by Wendy Adonyi

Q

Penicillin action

A

bactericidal, inhibit cell wall synthesis

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Q

Penicillin spectrum

A

G+

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Q

Penicillin toxicities

A

do not use in rodents

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Q

Ampicillin/amoxicillin action

A

bactericidal, inhibit cell wall synthesis

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Q

Ampicillin/amoxicillin spectrum

A

broad

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Q

Ampicillin/amoxicillin toxicities

A

vomiting

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Q

Cephalosporins action

A

bactericidal, inhibit cell wall synthesis

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Q

Cephalosporins spectrum

A

4 generations, narrow to broad depending on generation

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Q

Cephalosporins toxicities

A

GIT upsets

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Q

Tetracycline action

A

bacteriostatic, inhibits protein synthesis

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Q

Tetracycline spectrum

A

broad

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Q

Tetracycline toxicities

A

discoloration of teeth

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Q

doxycycline action

A

bacteriostatic, inhibits protein synthesis

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Q

doxycycline spectrum

A

broad

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Q

doxycycline toxicities

A

esophageal strictures in cats

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Q

Sulfonamides action

A

bacteriostatic, antimetabolite

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Q

Sulfonamides toxicities

A

crystalluria

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Q

TMP sulfa action

A

bactericidal

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Q

TMP sulfa spectrum

A

broad

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Q

TMP sulfa toxicities

A

KSC in dogs

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Q

Aminoglycosides action

A

bacteriostatic, inhibits protein synthesis

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Q

Aminoglycosides spectrum

A

G-

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Q

Aminoglycosides toxicity

A

nephrotoxicity

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Q

Gentamicin toxicity

A

ototoxicity

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Q

what class of drugs is gentamicin

A

Aminoglycosides

Q

Lincosamides action

A

bacteriostatic, inhibits protein synthesis

Q

Lincosamides spectrum

A

G+

Q

Lincosamides toxicity

A

GIT toxicity

Q

Macrolides action

A

bacteriostatic, inhibits protein synthesis

Q

Macrolides spectrum

A

variable

Q

Macrolides toxicity

A

GIT toxicity

Q

what class does Erythromycin belong to

A

Macrolides

Q

what class does Tilmicosin belong to

A

Macrolides

Q

what class does Azithromycin belong to

A

Macrolides

Q

Tilmicosin toxicity

A

Fatal if injected into humans

Q

Fluoroquinolones action

A

bactericidal, inhibits DNA synthesis

Q

Fluoroquinolones spectrum

A

broad

Q

Enrofloxacin belongs to what class

A

Fluoroquinolones

Q

Enrofloxacin toxicities

A

interfere with cartilage in puppies
Retinal damage in cats

Q

Polypeptide Antibiotics be given IM?

A

no, can only give topically

Q

Polymyxin B belongs to what class

A

Polypeptide Antibiotics

Q

Bacitracin belongs to what class

A

Polypeptide Antibiotics

Q

Polymyxin B action

A

bactericidal, affects cell wall

Q

Polymyxin B spectrum

A

G-

Q

Bacitracin action

A

bactericidal, affects cell wall

Q

Bacitracin spectrum

A

G+

Q

Chloramphenicol action

A

bscteriostatic, affects protein synthesis

Q

Chloramphenicol spectrum

A

broad

Q

Chloramphenicol toxicities

A

aplastic anemia - can’t use in food animals

Q

Florphenicol belongs to what class

A

Chloramphenicol

Q

what antimicrobial is ok in food animals

A

Florphenicol

Q

Nitrofurans action

A

Bactericidal Inhibit CHO metabolism

Q

Nitrofurans spectrum

A

broad

Q

Nitrofurans toxicity

A

toxic if used parenterally
human carcinogen
can’t use in food animals

Q

Nitroimidazole action

A

Bactericidal Inhibit DNA synthesis

Q

Nitroimidazole spectrum

A

Narrow

Q

Nitroimidazole toxicity

A

can’t use in food animals

Q

Metronidazole belongs to what class

A

Nitroimidazole

Q

Metronidazole spectrum

A

anaerobes
Giardia

Q

Metronidazole toxicity

A

neurologic toxicity