antimicrobial Flashcards

1
Q

Penicillin action

A

bactericidal, inhibit cell wall synthesis

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2
Q

Penicillin spectrum

A

G+

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3
Q

Penicillin toxicities

A

do not use in rodents

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4
Q

Ampicillin/amoxicillin action

A

bactericidal, inhibit cell wall synthesis

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5
Q

Ampicillin/amoxicillin spectrum

A

broad

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6
Q

Ampicillin/amoxicillin toxicities

A

vomiting

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7
Q

Cephalosporins action

A

bactericidal, inhibit cell wall synthesis

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8
Q

Cephalosporins spectrum

A

4 generations, narrow to broad depending on generation

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9
Q

Cephalosporins toxicities

A

GIT upsets

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10
Q

Tetracycline action

A

bacteriostatic, inhibits protein synthesis

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11
Q

Tetracycline spectrum

A

broad

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12
Q

Tetracycline toxicities

A

discoloration of teeth

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13
Q

doxycycline action

A

bacteriostatic, inhibits protein synthesis

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14
Q

doxycycline spectrum

A

broad

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15
Q

doxycycline toxicities

A

esophageal strictures in cats

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16
Q

Sulfonamides action

A

bacteriostatic, antimetabolite

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17
Q

Sulfonamides toxicities

A

crystalluria

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18
Q

TMP sulfa action

A

bactericidal

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19
Q

TMP sulfa spectrum

A

broad

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20
Q

TMP sulfa toxicities

A

KSC in dogs

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21
Q

Aminoglycosides action

A

bacteriostatic, inhibits protein synthesis

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22
Q

Aminoglycosides spectrum

A

G-

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23
Q

Aminoglycosides toxicity

A

nephrotoxicity

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24
Q

Gentamicin toxicity

A

ototoxicity

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25
Q

what class of drugs is gentamicin

A

Aminoglycosides

26
Q

Lincosamides action

A

bacteriostatic, inhibits protein synthesis

27
Q

Lincosamides spectrum

A

G+

28
Q

Lincosamides toxicity

A

GIT toxicity

29
Q

Macrolides action

A

bacteriostatic, inhibits protein synthesis

30
Q

Macrolides spectrum

A

variable

31
Q

Macrolides toxicity

A

GIT toxicity

32
Q

what class does Erythromycin belong to

A

Macrolides

33
Q

what class does Tilmicosin belong to

A

Macrolides

34
Q

what class does Azithromycin belong to

A

Macrolides

35
Q

Tilmicosin toxicity

A

Fatal if injected into humans

36
Q

Fluoroquinolones action

A

bactericidal, inhibits DNA synthesis

37
Q

Fluoroquinolones spectrum

A

broad

38
Q

Enrofloxacin belongs to what class

A

Fluoroquinolones

39
Q

Enrofloxacin toxicities

A

interfere with cartilage in puppies
Retinal damage in cats

40
Q

Polypeptide Antibiotics be given IM?

A

no, can only give topically

41
Q

Polymyxin B belongs to what class

A

Polypeptide Antibiotics

42
Q

Bacitracin belongs to what class

A

Polypeptide Antibiotics

43
Q

Polymyxin B action

A

bactericidal, affects cell wall

44
Q

Polymyxin B spectrum

A

G-

45
Q

Bacitracin action

A

bactericidal, affects cell wall

46
Q

Bacitracin spectrum

A

G+

47
Q

Chloramphenicol action

A

bscteriostatic, affects protein synthesis

48
Q

Chloramphenicol spectrum

A

broad

49
Q

Chloramphenicol toxicities

A

aplastic anemia - can’t use in food animals

50
Q

Florphenicol belongs to what class

A

Chloramphenicol

51
Q

what antimicrobial is ok in food animals

A

Florphenicol

52
Q

Nitrofurans action

A

Bactericidal Inhibit CHO metabolism

53
Q

Nitrofurans spectrum

A

broad

54
Q

Nitrofurans toxicity

A

toxic if used parenterally
human carcinogen
can’t use in food animals

55
Q

Nitroimidazole action

A

Bactericidal Inhibit DNA synthesis

56
Q

Nitroimidazole spectrum

A

Narrow

57
Q

Nitroimidazole toxicity

A

can’t use in food animals

58
Q

Metronidazole belongs to what class

A

Nitroimidazole

59
Q

Metronidazole spectrum

A

anaerobes
Giardia

60
Q

Metronidazole toxicity

A

neurologic toxicity