Uworld Set 4 Flashcards

1
Q

glomerulonephritis showing erythrocyte casts proteinuria hypertension following sunburn with significantly low complement

A

SLE

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2
Q

what is the cause for CNS findings associated with SLE

A

vasculitis

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3
Q

fever rash eosinophilia with blood cell casts and eosinophiluria

A

drug induced interstitial nephritis

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4
Q

ear nose throat and pulmonary vasculitis

A

granulomatosis with polyangiitis

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5
Q
pruritus
fatigue
hepatomegaly
elevated serum bilirubin
positive antimitochondrial antibody
A

primary biliary cholangitis

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6
Q

three main testable complications of Primary biliary cholangitis

A

nutritional deficiency
hepatocellular carcinoma
osteomalacia

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7
Q

why is ascending cholangitis NOT associated with primary biliary chalangitis

A

it is an intrahepatic destruction of bile ducts not extrahepatic

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8
Q

what is the difference between primary biliary cholangitis and primary sclerosing cholangitis

A

PBC is only intrahepatic
PSC is both intra and extra
PSC is associated with inflammatory bowel disease and colonic cancer
PBC is associated with antimitochondrial antibodies and hepatocellular carcinoma

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9
Q

nausea and vomiting
pneumobilia
hyperactive bowel sounds
dilated loops of bowels

A

gallstone ileus

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10
Q

hypercapneic patients with poor mental status
hemodynamic instability
profound acidemia

A

intubation

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11
Q

how long should NPPV be trialed in acute exacerbation of COPD patients prior to intubation

A

2 hours

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12
Q

pertinent history for patients with absence seizures

A

prior febrile seizures

family history of seizure disorder

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13
Q

absence seizure patients are at increased risk for

A

ADHD

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14
Q

what tumors are seen in association with tuberous sclerosis

A

cardiac rhabdomyosarcoma

renal angiomyolipoma

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15
Q

intermittent muscle weakness triggered by strong emotions

A

cataplexy

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16
Q

optic gliomas associated with what disorder

A

neurofibromatosis type I

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17
Q

low B cell counts are a feature of

A

X linked bruton agammaglobulinemia

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18
Q

CGD patients would see recurrent infections with what two commonly tested bugs

A

staph aureus

aspergillus

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19
Q

lab values that are crucial in diagnosis of splenic sequestration in a sickle cell patient

A

normocytic anemia
high retic count
low hgb/hct
low platelets

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20
Q

reticulocyte count very low, platelets normal in a sickle cell patient following viral illness

A

parvovirus B19

sickle cell aplastic crisis

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21
Q

thymoma found in what part of the mediastinum

A

anterior

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22
Q

retrosternal thyroid teratoma and lymphoma

A

anterior mediastinum

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23
Q

all neurogenic tumors are located in what portion of the mediastinum

A

posterior

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24
Q

bronchogenic cysts are in what portion of the mediastinum

A

middle

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25
Q

thymoma associated with what disease

A

myasthenia gravis

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26
Q

treatment for stable ectopic pregnancy

A

methotrexate

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27
Q

what are the three most common secondary causes of digital clubbing

A

occult lung malignancy
CF
right to left shunting

28
Q

megakaryocytes releasing PDGF and VEGF in the fingers can lead to

A

digital clubbing

29
Q

digital clubbing in individuals with COPD should prompt a search for

A

occult malignancy

30
Q

basal ganglia or putamenal hemorrhage usually 2/2

A

hypertension

31
Q

what are the arteries that are implicated in hypertensive intraparenchymal bleeds AKA charcot bouchard aneurysms

A

lenitculostriate arteries

32
Q

most common cause of spontaneous lobar/cortical hemorrhager (occipital, parietal)

A

cerebral amyloid angiopathy

33
Q

MCC for intraparenchymal brain hemorrhage in children

A

AVM

34
Q

MCC for subarachnoid hemorrhage in adults

A

berry aneurysm rupture

35
Q

black box warning associated with propylthiouracil in treatment of hypertension

A

liver injury

36
Q

most serious side effect of anti thyroid drugs

A

agranulocytosis

37
Q

which treatment for hyperthyroidism can worsen ophthalmopathy seen in graves’ disease

A

radioactive iodine therapy

38
Q

injury to shoulder in which there is decreased passive and active motion

A

adhesive capsulitis

39
Q

condition of thumb injury in new mothers that hold their babies outstretched with thumbs upright

A

de quervain tenosynovitis

40
Q

pain with radial flexion of the wrist and point tenderness over the trapezium

A

flexor carpi radialis tenosynovitis

41
Q

should be considered for patients with an MS who do not respond to corticosteroids

A

plasmapharesis

42
Q

muscle relaxant used to calm spasms in MS

A

baclofen

43
Q

merdication commonly tested that decreases recurrence of MS used in chronic maintenance therapy

A

interferon Beta

44
Q

medial knee pain and focal tenderness without trauma

A

pes anserinus pain syndrome

45
Q

valgus stress test illiciting pain indicates

A

medial collateral ligament

46
Q

what is the mechanism by which shock occurs in severe acute pancreatitis

A

release of inflammatory markers by the pancreas leads to vasodilation and increased capillary permeability leading to massive fluid extravasation into the space surrounding the pancreas

47
Q

inferior and posterior wall MI

artery most likely involved

A

right coroanry

48
Q

most likely artery involved in inferior wall MI

A

RCA

49
Q

what is the reason for heart block accompanying RCA MI

A

damage to the AV node

50
Q

patients that are high risk for toxic megacolon

A

IBD

51
Q

drugs preferred for IBD associated toxic megacolon

A

corticosteroids

52
Q

toxic megacolon in HIV patient

A

CMV

53
Q

if diagnosis of pancreatitis is still unclear after lab testing

A

CT

54
Q

3 main situations in which ERCP can be utilized

A
biliary pancreatitis (can decrease morbidity and mortality)
chronic recurrent pancreatitis
draining pancreatic pseudocysts
55
Q

medication used specifically for aspergillosis

A

voriconizole

56
Q

treatment for a mother with HIV and viral load greater than 1000 at the time of delivery

A

c section and zidovudine

57
Q

drug administered to baby for 6 weeks following birth to HIV mother

A

zidovudine

58
Q

expansion of CGG repeats

A

fragile X

59
Q

fragile X syndrome has aspects of what two disorders

A

ADHD

autism

60
Q

aractnodactyly most commonly found in

A

marfans

61
Q

common syndromic cause of gynecomastia in males

A

klinefelters

62
Q

hemihyperplasia associated with

A

beckwith wiedemann

63
Q

macroglossia
omphalocele
hypoerinsulinism

A

beckwith weidemann

64
Q

obesity in the setting of intellectual disability in children

A

prader willi

65
Q

thin vermillion border
palpable fissures
thin philtrum

A

fetal alcohol syndrome

66
Q

stroke in a kid

A

SCD

67
Q

confirmation of stroke in a kid with SCD

A

MRI