Uworld 3 Flashcards

1
Q

blood type antibodies

A

IgM

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2
Q

PSGN what deposits?

A

IgG, IgM, C3

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3
Q

Schistosomiasis- from what animal?

A

snail

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4
Q

majority of overdoses from what?

A

opiates

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5
Q

AST increase w/out accompanying ALT

A

suggests MI

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6
Q

proliferative stimuli for atherosclerotic plaque?

A

platelets

PDGF

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7
Q

zinc fingers- what hormones?

A

lipid soluble (transcription factors)

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8
Q

loss of 2,3 BPG binding –>

A

increased O2 affinity like fetal Hg

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9
Q

Airway epithelium transition. Last thing to disappear?

A

cilia

need to get mucous out

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10
Q

sickle cell disease osteomyelitis from what?

A

think salmonella
capsule
resists opsonization

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11
Q

dihydropyridines

A

end in -ine
increase peripheral vasodilation
rx HTN w/o cardiac effects

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12
Q

pneumonia in alcoholic

A

klebsiella

use ceftriaxone

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13
Q

prognosis in melanoma is strongly determined by

A

depth of the lesion

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14
Q

test to determine Rh incompatibility

A

indirect Coombs test to detect IgG antibody

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15
Q

t(9,22)

A

BCR-ABL
Philadelphia chromosome

CML

increased neutrophils, metamyelocytes (immature neutrophils) and basophilia

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16
Q

Rathke pouch (anterior pituitary) from what embryologic layer?

A

surface ectoderm

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17
Q

budding yeast that forms germ tubes at 37 degrees?

A

candida

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18
Q

influenza viruses = orthomyxovirus, how create new strains?

A

genetic reassortment of RNA segments

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19
Q

Portocaval anastamoses

A

Left gastric –> esophageal
Superior rectal –> middle and inferior rectal
paraumbilical–> superficial and inferior epigastric

20
Q

parotid gland tumor –>

A

facial droop

21
Q

digoxin toxicity

A

Color Vision Changes *

arrhythmias

anorexia, nausea, vomiting, pain
fatigue, confusion, weakness

22
Q

vWF binds to what?

23
Q

sickle cell protein change

A

valine for glutamic acid

24
Q

pull undescended testicle through what?

A

external oblique aponeurosis

25
malignant otitis externa in elderly diabetics
pseudo aeruginosa non lactose fermenting ox pos gram neg rod
26
caudal regression syndrome
agenesis of sacrum/ lumbar | poorly controlled maternal diabetes
27
arginine- what cycle
urea
28
diet of carbs and proteins. What increases to inhibit beta oxidation?
malonyl CoA inhibits carnitine acyl transferase
29
sign of insulin resistance
increased waist circumference
30
treat specific phobia (elevators)
behavioral
31
centriacinar emphysema pathogenesis
macrophages and neutrophils release proteases that degrade ECM
32
candida causes include
tobacco
33
what makes elastase in lungs?
alveolar macrophages
34
what makes secretin?
S cells of duodenum
35
absence of vas def- what condition?
cystic fibrosis
36
highest O2 content of fetal circ
umbilical vein --> liver--> IVC
37
collagen hydroxylation (vit C) happens where?
RER
38
what keeps strep from phagocytosis?
protein M
39
failed lateral fusion of paramesonephric ducts (= mullerian ducts) -->
bicornate uterus mesonephric ducts don't fuse
40
west nile
febrile, rash, encephalitis, flaccid paralysis RNA flavivirus
41
aldolase B defish, remove what from diet?
sucrose
42
osteocytes connected to ea other by
gap jxns
43
H flu grows well w/ staph aureus why?
provides NAD+
44
obesity lung disease
restrictive
45
turner syndrome infertility
ovarian failure | use IVF
46
Rx for preggo with DVT
enoxaparin | LMWHs don't cross placenta