comlex Flashcards
Porphyria cutanea tarda. What enzyme is missing?
- most common porphyria
pohtosensitive –> blistering
deficiency in uroporphyrinogen decarboxylase -> uroporphyrin accumulates in the urine
exacerbated by alcohol
reciprocal inhibition
uses the reflex relaxation of the agonist muscle when the antagonist muscle is contracted
alkaptonuria
metabolic disorder –> black discoloration of cartilage, arthritis, and dark urine
caused by autosomal recessive deficiency of homogentisic acid oxidase
most congenital enzyme deficiencies inherited how?
autosomal recessive
methimazole complications
agranulocytosis –> increased infections
treatment for hyperthyroidism
what statistical test do we use for 2 groups with an interval variable?
t-test
periorbital cellulitis can –>
cavernous sinus thrombosis
achalasia
malfunction of the myenteric nerve plexus within the muscle of the esophagus –> no peristaltic wave
why does asthma get better with age?
airways increase in caliber
constrictive pericarditis
thickened, fibrotic pericardium
increased JVP, Kussmaul sign, rapid y descent, pericardial knock, hepatomegaly, ascites, fatigue, peripheral edema
causes: radiation, TB, infections, prior surgery, MI, pulmonary asbestosis, chronic renal failure, connective tissue disorders, neoplastic pericardial infiltration.
Transthoracic echocardiogram will show it
what do we give for tourettes?
haloperidol.
typical antipsychotics (haloperidol and fluphenazine) and atypical ones (risperidone, olanzapine, pimozide) decrease the severity of tics in Tourette syndrome.
psoas syndrome goes with
contralateral piriformis spasm
posterior sacral torsion
contralateral compensatory pelvic shift
ipsilateral pseudosciatica
how do we test if heparin is working well?
activated partial thromboplastin time
INR and prothrombin time are used for warfarin, etc.
ZES most common tumor site?
pancreas
waiter’s tip
= erb’s palsy
cervical roots C5 and C6
spondylolysis
defect in the pars interarticularis
scotty dog collar
caused by stress fracture, etc.