UW 3 Flashcards
Elderly pt w/dehydration tx?
IV sodium fluids:
0.9% NS or
Crystalloid
Complication with rehydration of elderly pt?
Sodium loading can unmask subclinical heart failure
Heavy proteinuria, rapidly progressive development of renal failure in HIV + pt?
Focal Segmental Glomerulosclerosis (Collapsing type)
- Azotemia
- Normal sized kidneys
Air under the diaphragm? Tx?
Perforated viscus
Immediate surgery -> emergent exploratory laparotomy
Pt presents w/severe epigastric pain, N/V after eating?
Perforated peptic ulcer.
Look for pneumoperitoneum
When do we check for Gestational DM in pregnancy (GDM)?
24-28 wks
What is tx for GDM?
- Dietary modifications/Exercise
2. Insulin - does not cross placenta
What is goal glucose during pregnancy?
Fasting blood sugars < 95 mg/dL
1 hour postprandial level of < 140 mg/dL
2 hour level < 120 mg/DL
Complications of maternal hyperglycemia seen in 2nd and 3rd trimester?
Persistent -> fetal hyperglycemia -> fetal hyperinsulinemia -> Fetal hypoxemia -> polycythemia
Hypoglycemia
Organomegaly
Macrosomia - shoulder dystocia
Complications of maternal hyperglycemia in 1st trimester?
- Congenital anomalies
- small colon syndrome
- NTDs
- Congenital heart dz - Spontaneous Abortions
Most likely cause of neonate with thyrotoxicosis with mother w/Graves treated with surgery and meds?
Persistence of thyroid stimulating immunoglobulin in mother
Maternal - post thyroidectomy, TSI levels remain high for months; TSI Autoabs can cross placenta
Etiology of Lambert eaton?
AutoAbs to voltage-gated Calcium channel
Presynaptic motor nerve terminal
Receptors involved in myasthenia graves?
DTRs in MG?
Postsynaptic Ach receptors
DTRs usually preserved
Multicentric CNS inflammation and demyelination?
Multiple Sclerosis
Rash seen in pellagra?
Resembles sun burn
Bilateral and symmetric
Progresses to become hyperpigmented and thickened
Diaphragmatic hernia presentation?
MC on left side - left side displaces/impairs left lung growth ->absent left side breath sounds
- Deviation of heart into Right thorax -> impairs right lung growth - right lung aeration and right sided heart sounds
Pulmonary hypoplasia and pulmonary HTN
Polyhydramnios b/c of esophageal compression
Concave abdomen and barrel shaped chest on PE
Scaphoid abdomen and respiratory distress?
Diaphragmatic hernia
Dx testing for diaphragmatic hernia
CXR to look for loops of bowel in chest
Tx for diaphragmatic hernia
Immediate intubation
Naso or orogastric tube for suction
Place umbilical arterial line for ABG and BP
Place umbilical venous catheter for IVF and meds
Surgical correction
VSD seen in which groups?
Trisomy 13, 18, 21
Heart defect common in Trisomy 21?
Endocardial cushion defect
ASD
Heart defects seen in CATCH-22, DiGeorge, and velocardiofacial syndromes?
Conotruncal - Truncus arteriosus, tet of fallot, interrupted aortic arch
Cryptochidism is ass’d with what complications despite orchiopexy?
Subfertility
Testicular cancer
Risk of testicular torsion with cryptochidsm post orchiopexy?
NO, b/c testis is surgically affixed to scrotal wall
Dose-limiting side effect of hydroxyurea?
Myelosuppression - neutropenia, thrombocytopenia