UW 3 Flashcards
Elderly pt w/dehydration tx?
IV sodium fluids:
0.9% NS or
Crystalloid
Complication with rehydration of elderly pt?
Sodium loading can unmask subclinical heart failure
Heavy proteinuria, rapidly progressive development of renal failure in HIV + pt?
Focal Segmental Glomerulosclerosis (Collapsing type)
- Azotemia
- Normal sized kidneys
Air under the diaphragm? Tx?
Perforated viscus
Immediate surgery -> emergent exploratory laparotomy
Pt presents w/severe epigastric pain, N/V after eating?
Perforated peptic ulcer.
Look for pneumoperitoneum
When do we check for Gestational DM in pregnancy (GDM)?
24-28 wks
What is tx for GDM?
- Dietary modifications/Exercise
2. Insulin - does not cross placenta
What is goal glucose during pregnancy?
Fasting blood sugars < 95 mg/dL
1 hour postprandial level of < 140 mg/dL
2 hour level < 120 mg/DL
Complications of maternal hyperglycemia seen in 2nd and 3rd trimester?
Persistent -> fetal hyperglycemia -> fetal hyperinsulinemia -> Fetal hypoxemia -> polycythemia
Hypoglycemia
Organomegaly
Macrosomia - shoulder dystocia
Complications of maternal hyperglycemia in 1st trimester?
- Congenital anomalies
- small colon syndrome
- NTDs
- Congenital heart dz - Spontaneous Abortions
Most likely cause of neonate with thyrotoxicosis with mother w/Graves treated with surgery and meds?
Persistence of thyroid stimulating immunoglobulin in mother
Maternal - post thyroidectomy, TSI levels remain high for months; TSI Autoabs can cross placenta
Etiology of Lambert eaton?
AutoAbs to voltage-gated Calcium channel
Presynaptic motor nerve terminal
Receptors involved in myasthenia graves?
DTRs in MG?
Postsynaptic Ach receptors
DTRs usually preserved
Multicentric CNS inflammation and demyelination?
Multiple Sclerosis
Rash seen in pellagra?
Resembles sun burn
Bilateral and symmetric
Progresses to become hyperpigmented and thickened
Diaphragmatic hernia presentation?
MC on left side - left side displaces/impairs left lung growth ->absent left side breath sounds
- Deviation of heart into Right thorax -> impairs right lung growth - right lung aeration and right sided heart sounds
Pulmonary hypoplasia and pulmonary HTN
Polyhydramnios b/c of esophageal compression
Concave abdomen and barrel shaped chest on PE
Scaphoid abdomen and respiratory distress?
Diaphragmatic hernia
Dx testing for diaphragmatic hernia
CXR to look for loops of bowel in chest
Tx for diaphragmatic hernia
Immediate intubation
Naso or orogastric tube for suction
Place umbilical arterial line for ABG and BP
Place umbilical venous catheter for IVF and meds
Surgical correction
VSD seen in which groups?
Trisomy 13, 18, 21
Heart defect common in Trisomy 21?
Endocardial cushion defect
ASD
Heart defects seen in CATCH-22, DiGeorge, and velocardiofacial syndromes?
Conotruncal - Truncus arteriosus, tet of fallot, interrupted aortic arch
Cryptochidism is ass’d with what complications despite orchiopexy?
Subfertility
Testicular cancer
Risk of testicular torsion with cryptochidsm post orchiopexy?
NO, b/c testis is surgically affixed to scrotal wall
Dose-limiting side effect of hydroxyurea?
Myelosuppression - neutropenia, thrombocytopenia
Indomethacin CI in who?
Renal Failure
Hx of GI bleeds
Are gallstones radiolucent or opaque?
80% radiolucent
Best initial test for Cholelithiasis?
Abdominal US
Tx for symptomatic GB Dz?
Laparoscopic cholecystectomy
When do we do ERCP?
Cholangitis
Biliary obstruction with a stone
When do we do HIDA scan?
Confirmation for acute cholecystitis
- esp acalculous type
Most frequently injured organs in BAT?
Liver
Spleen
Free intraperitoneal fluid after BAT?
Splenic Laceration
HypoTN after BAT is suggestive of?
Solid organ or vascular injury
Next step in hemodynamically unstable pt w/evidence of free intraperitoneal fluid on US?
Emergency surgical exploration
When do we see bladder rupture?
Lower abdominal trauma w/pelvic fx where bony fragments damage and rupture bladder
Signs of pelvic trauma?
Pelvic pain, tenderness
When do we see rupture/tear of descending aorta?
Chest trauma from deceleration injuries
When do we see small bowel injury in trauma?
GSW
Stab wound
Tx for bacterial vaginosis in pregnancy?
Oral Metronidazole
- same for non-pregnant
- Vaginal metronidazole and clindamycin - alternatives
Tx for HSV in pregnancy?
Acyclovir = Risk to fetus greater than risk of tx
Tx for Candidiasis in pregnancy?
Fluconazole
Are macrolides safe in pregnancy?
Azithromycin - Yes
Erythromycin estolate - NO. CI b/c causes acute cholestatic hepatitis
Presentation of psoas abscess
Fever
Lower abdominal or back pain
Dx for Intraabdominal abscess?
Psoas abscess - Deep abdominal palpation elicits tenderness = psoas muscle deep on posterior abd wall
CT scan
High clinical suspicion of psoas abscess with negative CT?
Exploratory Laparatomy
Dense intramembranous deposits that stain for C3?
Membranoproliferative glomerulonephritis
- caused by IgG abs
C3 nephritic factor?
IgG abs directed against C3 convertase of alternative complement pathway
- Abs react w/C3 convertase and lead to persistent complement activation and kidney damage
Cell mediated injury seen in what glomerular dz?
Idiopathic crescenteric glomerulonephritis
Hypertensive intracranial hemorrhage occurs most commonly in what part of brain?
Basal ganglia
Pons
Thalamus
Cerebellum
Presentation of hypertensive intracranial hemorrhage
Initial - Mc in BG/Cerebellum/thalamus/pons
Progress - focal sx’s (hemiplegia, hemiparesis)
ICP -vomiting, HA
Strongest influence on long term prognosis after STEMI?
Restoration of coronary blood flow
What factors determine myocardial oxygen demand?
Heart rate
Preload
Afterload
Contractility
Pt presents with HTN and Hypokalemia - next best step?
Plasma Aldosterone/Renin Ratio:
- Elevated - Adrenal suppression tets
- Positive - Adrenal imagining
Sticking sensation in throat, dysphagia w/heartburn, Manometry - absence of peristaltic waves in lower 2/3 esophagus, significant decrease in LES tone?
Scleroderma - esp absence of peristaltic waves = not seen in GERD
What can severe coughing paroxysms result in?
Subcutaneous emphysema - air leaking from chest wall to subcutaneous tissues, can lead to pneumothorax
Subcutaneous emphysema secondary to cough, what test must be done?
CXR to r/o pneumothorax
Which marker is indicative of infectivity in Hep B?
HBsAg
Hepatitis B marker for successful vaccination or clearance?
Anti-HBs
Hep B marker indicative for noninfectivity?
Anti-HBs
Marker that indicates active viral replication?
HBeAg
Marker suggests cessation of active viral replication and low infectivity?
Anti-HBe
Best screening for acute hepatitis?
HBsAg
anti-HBc
What is glucose testing in pregnancy?
Glucose load test -non fasting: 50 g then test 1 hr later = 140, then do glucose tolerance test. if any high, then DM confirmed.