Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Complete Review Course > Uveitis Vol. 2 > Flashcards

Uveitis Vol. 2 Flashcards

1
Q

What type of bacteria is associated with LPS endotoxin?

A

Gram-negative bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What protein is responsible for most of the inflammatory effects of LPS?

A

Lipid A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of immune response is directed against LPS?

A

Innate immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the major cause of shock, fever, and sepsis in gram-negative infections?

A

LPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What type of immune response is associated with Type I hypersensivity?

A

Anaphylactoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What type of immune response is associated with Type II hypersensivity?

A

Cytotoxic antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of immune response is associated with Type Ill hypersensivity?

A

Immune complex reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What type of immune response is associated with Type IV hypersensivity?

A

Cell-mediated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What type of immune response is associated with Type V hypersensivity?

A

Stimulatory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is function of the Fe portion of antibodies?

A

Attachment site of effector cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are idiotopes?

A

Anitgenic sites on antibodies that other antibodies can bind to

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are idiotypes?

A

Antibodies to idiotopes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the most common immunoglobin found in the serum?

A

lgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What type of antibody crosses the placenta?

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What type of antibody is associated with mast-cell degranulation?

A

IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a classic example of antibody complex binding that activates the complement cascade by the membrane attack complex?

A

Hemolytic anemia of the newborn (eg. due to Rh incompalibilty)

17
Q

What is the most commonly type of cancer associated with cancer-associated retinopathy?

A

Small-cell lung cancer

18
Q

What causes cancer-associated retinopathy?

A

Antibody mediated cross-reaction between tumor antigens and ocular autoantigens

19
Q

What is Goldmann-Witmer coefficient used to measure?

A

Ratio of intraocular localantibody production compared to serum antibody production

20
Q

What autoantigen is associated with Wegener granulomatosis?

A

Proteinase-3

21
Q

What is the function of IFN-gamma and TNF-B?

A

Activation of macrophages

22
Q

What type of cells are CD8 cytotoxic T-cells especially good at killing?

A

Tumor cells and virus infected cells

23
Q

What is the function of CD951igand (Fasl)?

A

Cell-programmed death (eg. apoptosis)

24
Q

What is primary type of immune reaction in sympathetic ophthalmia?

A

Th1 delayed-hypersensitivity response

25
Q

What autoantigens are thought to be responsible for sympathetic ophthalmia?

A

Retinal or uveal antigens

26
Q

What is the most frequent opportunistic ocular infection in patients with AIDS?

A

CMV

27
Q

What type of delayed hypersensitivity response is thought to play a role in allergic conjunctivitis?

A

Th2-mediated delayed hypersensitivity

28
Q

Which type of immunity typically activates the classical complement pathway?

A

Adaptive immunity

29
Q

Which type of immunity typically activates the alternative complement pathway?

A

Innate immunity

30
Q

What are the principal complement-derived immune mediators?

A

Anaphylatoxins

31
Q

What complement factor is responsible for opsonization?

A

C3b

32
Q

What is the primary role of the Hageman factor-dependent pathway?

A

Activation of kinins

33
Q

What enzyme is responsible for the activation of kinins?

A

Kallikrein

34
Q

What enzyme converts fibrinogen to fibrin?

A

Thrombin

35
Q

What enzyme is responsible for degradation of fibrin?

A

Plasmin

36
Q

What is the principle source of serotonin?

A

Platelets

37
Q

What two types of cells release histamine?

A

Mast cells and basophils

38
Q

What is the primary function of cyclooxygenase?

A

Conversion of arachidonic acid to PGG2

39
Q

What type of immune mediators are thought to play a role in cystoid macular edema associated with anterior segment surgery or trauma?

A

Prostaglandins

Complete Review Course (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions