Pathology Volume 1 Flashcards
What cells are the tissue bound equivalent of blood borne basophils?
Mast calls
What type of giant cell is characterized by a horseshoe arrangement of the nuclei?
Langhans cells
What type of giant cells if associated with an annulus of nuclei surrounded by a lipid-filled clear zone?
Touton giant cells
What type of giant cell is associated with haphazardly arranged nuclei?
Foreign body giant cells
What type of immune call is associated with an eccentric “cartwheel” or “clockface” nucleus and perinuclear halo?
Plasma cell
What is the tissue of origin of a sarcoma?
Soft tissue
What type of tumor is associated with small, round, blue cells?
Retinoblastma
How long does complete healing of a corneal abrasion take, including reformation of anchoring fibrils?
4 to 6 weeks
By what process does the corneal stroma heal?
Fibrosis
What layer of the cornea does not regenerate if damaged?
Bowman’s membrane
What are the two glycosaminoglycans of the cornea?
Keratin sulfate and chondroitan sulfate
What glycosaminoglycan is found in the sclera?
Chondroitin sulfate
Name two ways that cyclodialysis can cause hypotony.
- Aqueous leak into the suprachoroidal space 2. Decreased aqueous production
What causes cyclodialysis?
Disinsertion of the longitudinal muscle from the scleral spur
What causes traumatic recession of the anterior chamber angle?
Rupture of the face of the ciliary body
Where is retinal dialysis most likely to occur?
Inferotemporal or superonasal quadrant
What determines the borders of a choroidal hemorrhage?
Location of the vortex veins and scleral spur
What causes iridodialysis?
Separation of the iris root at the thinnest portion of the diaphragm
Name two complications of choroidal rupture.
- CNV 2. Granulomatous inflammation
What causes choroidal rupture?
Break in Bruch’s membrane due to trauma
Where is commotio retinae typically most prominent?
Macula
What causes the opaque retina of commotio retinae?
Disruption of the architecture of the photoreceptor elements
What is the retina attached to at the ora serrata?
Nonpigmented epithelium of the pars plana
How long does it take for hemosiderin to form following hemorrhage?
72 hours after hemorrhage
What causes sclopetaria?
Chorioretinal rupture and necrosis
What stage of atrophy is associated with “squared-off’’ configuration of the globe?
Atrophic bulbi with shrinkage
What is the average diameter of an eye with phthisis bulbi?
16 to 19 mm
