UTI Flashcards

1
Q

What is an uncomplicated UTI

A

infection in Structural and neurologically normal Urinary tract

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2
Q

What is a complicated UTi

A

infection in urinary tract with functional or structural abnormality e.g. in men, pregnant women, children, hospitalised

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3
Q

What are the causative organisms for UTI

A
E coli 
Proteus 
Klebsiella 
Enterococcus faecalis 
Staph saprophyticus 
Staph epidermidis
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4
Q

What are distinguishing features of Staph saprophyticus

A

coag negative

associated with infections in young woimen

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5
Q

What are distinguishing features of Staph epidermidis

A

presence of prosthesis (procedures, indwelling catheters

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6
Q

What are causes of obstruction to consider for UTI

A

Mechanical

Neurogenic

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7
Q

what are mechanical causes of obstruction in UTI?

A

extrarenal:
- valves, stenosis
- calculi
- BPH

renal:
- nephrocalcinosis
- nephropathy
- PKD

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8
Q

Whag are neurogenic causes of obstruction?

A

poliomyelitis
Diabetic neuropathy
Spinal cord injury

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9
Q

What is the issue caused by vescicoureteric reflux

A

maintains residual pool of urine after voiding in the bladder
This reflux causes scarring of kindeys

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10
Q

what pathogen causes abscess in the kidney?

A

S aureus

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11
Q

What are investigations for uncomplicated UTI

A

urine dip
MSU for MS&S
Bloods FBC, U&E, CRP

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12
Q

What are ix for complicated UTI

A

Renal USS

IV urography

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13
Q

When should you NOT do a dipstick for UTI

A

if patient is older than 65

because half of them will have bacteraemia regardless

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14
Q

Why are nitrites so specific for UTI

A

because they are produced by E coli

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15
Q

What does nitrite -ve, leukocyte +ve indicate

A

UTI caused by non-coliform bacterium

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16
Q

What is white cell pyuria indicative of

A

infection

17
Q

what is. squamous epithelial cell in urine culture indicative of

A

contamination

18
Q

What cutoff of organism copncentration is necessary for UTI dx

A

> 10^5 CFU/ml + urinary syptoms

CFU = colony forming units

19
Q

what do squamous epithelial cells look like on culture

A

fried egg appearance

20
Q

what organisms should you consider if prior pyuria (raised WBB, no growth on culture)

A

chlamydia trachomatis

21
Q

What agar is MC&S done on

A

chromogenic agar - turns different colour based on backteria

22
Q

What colour on agar suggests e coli

A

pink

23
Q

what colour on agar suggests coliforms

A

blue

24
Q

what colour on agar suggests gram +ve

A

light blue

25
Q

how can sampling for urine be done

A

MSU
catheter
suprapubic aspiration ( in young children)

26
Q

what antibiotic is given for uncomplicated UTI

A

cefalexin 500mg BD PO for 3 days

27
Q

What is the most likely cause of a candida UTI

A

indwelling catherer

28
Q

How do you tx candida UTI

A

remove catheter

no need for antifungal

29
Q

how do you treat pyelo

A

co-amoxiclav +/-gentamycin

30
Q

How do you manage uncomplicated UTI

A

Nitrofurantoin / Trimethoprim