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uterus Flashcards

Describe the common functional endometrial disorders (causes of AUB and DUB) Describe acute and chronic endometritis and the common causes and clinical associations. Describe the proposed causes and complications of endometriosis Describe adenomyosis and its associated clinicopathologic findings Describe endometrial polyps (symptoms, causes, outcomes) Describe the endometrial hyperplasia / carcinoma sequence Describe the common malignant tumors of the endometrium (endometrioid, clear cell

1
Q

bleeding due to alteration in the normal cyclical hormonal stimulation of the endometrium

A

dysfunctional uterine bleeding

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2
Q

causes of dysfunctional uterine bleeding

A

faiulre of ovulation
inadequate luteal phase
OCPs
menopausal changes

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3
Q

bleeding causes that are not considered dysfunctional uterine bleeding

A

polyp
hyperplasia/Carcinoma
endometriosis

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4
Q

causes of anovulatory cycles

A

excess estrogen

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5
Q

dysfunctional uterine bleeding associated with infertility and pregancy loss

A

inadequate luteal phase

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6
Q

dysfunctional uterine bleeding with low progesterone

A

inadequate luteal phase

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7
Q

endometriosis with neutrophils

A

acute

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8
Q

endometriosis with plasma cells

A

chronic

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9
Q

causes of acute endometriosis

A

birth, miscarrage, strep infection after retained products of conception

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10
Q

causes of chronic endometriosis

A

gonorrhea, chlamydia, IUD

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11
Q

most common locations of endometriosis

A

ovaries, pouch of douglas, peritoneal surfaces

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12
Q

likely cause of endometrosis

A

menstrual backflow through fallowian tubes

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13
Q

“chocolate cysts” and blood filled macrophages

A

endometriosis

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14
Q

growth of the endometrium into the mymetroum

A

adenomysosis

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15
Q

round muscular mass in uterus

A

adenomysosis

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16
Q

treatment for adenomysosis

A

hysterectomy

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17
Q

associated with tamifloxin

A

endometrial polyps

18
Q

chance endometrial polyps develops into cancer

A

very very slight

19
Q

time endometrial polyps develop

A

menopause most common

20
Q

presents with abnormal postmenipausal bleeding

A

endometrial hyperplasia

21
Q

endometrial hyperplasia with high risk of cancer

A

complex hyperplasia with atypia

22
Q

cancer risk of complex hyperplasia with atypia

A

20-40%

23
Q

histological sign of complex hyperplasia

A

atypical glands and more glands than stroma

24
Q

most common female GU tract cancer

A

endometrial carcinoma

25
Q

bigest risk for endometrial carcinoma

A

long term use of high-dose post menopausal estrogens

26
Q

most commin presentation of endometrial carcinoma

A

post-menopausal bleeds

27
Q

genetic mutation in endometrioid adenocarcinoma

A

PTEN

28
Q

gebetic mutation in papillary carcinoma

A

p53

29
Q

endometrial carcinoma automatically considered high grade

A

clear cell

30
Q

pasmmomoa bodies

A

serous adenocarcinoma (epithelial)

31
Q

adenocarcinoma of uterus spreads to

A

cervix

32
Q

serous endometrial carcinoma spreads to

A

pevis and abdomen

33
Q

treatment for adenocarcinoma of uterus

A

radiation

34
Q

treatment for serous endometrial carcinoma

A

chemo

35
Q

benign smooth muscle tumor of uterus

A

leimyoma

36
Q

common name for leimyoma

A

fibroid

37
Q

presentation of submucosal leiomyoma

A

menorrhagia

38
Q

presentation of subserosal leiomyoma

A

constipation and urinary urgency

39
Q

intersecting fascicles of begnin smooth muscle cells

A

leiomyoma

40
Q

most common sarcoma of uterus

A

leiomyosarcoma

41
Q

outcome for leiomyosarcoma

A

poor

42
Q

microscopy of leiomyosarcoma

A

increased cellularity, mitotic figures, cogaulative necreosis

GU (12 decks)

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