male GU pathology Flashcards

Describe the common developmental defects and congenital abnormalities of the penis and testis Describe phimosis, paraphimosis and their risk factors Describe the common inflammatory conditions that may affect the testis Compare and contrast common scrotal cysts Compare and contrast the cliniopathologic and prognostic features of the common testicular neoplasms Describe squamous neoplasia in regards to the penis

1
Q

abnormal opening of the urethra on the ventral shaft of the penis

A

hypospadias

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2
Q

abnormal opening of the urethra on the dorsal aspect of the penis

A

epispadsias

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3
Q

condition on which the foreskin cannot be retracted

A

phimosis

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4
Q

retracted foreskin cannot be pulled back over the glans penis

A

paraphimosis

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5
Q

risk factor of phimosis

A

inflamation of the prepuce (foreskin)

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6
Q

inflammation of the prepuce

A

balanoposthitis

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7
Q

failure of testicular descent into the scrotum

A

cryptoorchism

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8
Q

type of cancer found in cryptootchid testes

A

intratubular germ cell

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9
Q

most common type of neoplasm in the penis

A

squamous cell carcinoma

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10
Q

risk factors of penile SCC

A

poor hygeine, smokin, HPV 16 18

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11
Q

common presentation of penile SCC in situ

A

solitary plaque on older uncircumsized man

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12
Q

common presentation of invasive penile SCC

A

gray crusted papular lesion on glans or prepuce

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13
Q

most common cancer of testes

A

SCC

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14
Q

most common cause of scrotal enlargement

A

hydrocele

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15
Q

accumulation of fluid between tunica vaginais

A

hydrocele

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16
Q

accumulation of blood between tunica vaginais

A

hematoceles

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17
Q

accumulation of lymph between tunica vaginais

A

chyloceles

18
Q

grotesque swelling of scrotum

A

eliphantiasis

19
Q

effects of cryptoorchidism

A

sterility, atrophy, cancer

20
Q

causes of epididymitis/orchiditis

A

STI, UTI, mumps

21
Q

swollen and tender testes

A

orchididiits

22
Q

can elicit granulomatous inflammation in the testis

A

TB, autoimmune injury

23
Q

type of testicular torsion with underlying anatomical defect

A

adult

24
Q

peak age in testicular neoplasms

A

15-34

25
Q

nearly all postpubertal testicular cancers are

A

germ cell

26
Q

common benign testicular cancer

A

sex cord stromal

27
Q

major risk factor in testicular cancer

A

cryptoorchidsm, intersex syndromes, FMX, contralateral testes cancer

28
Q

genetic finding in testicular cancer

A

isochromosome of 12

29
Q

all of these cancers have elevated hCG

A

choriocarcinoma

30
Q

AFP marker in this cancer

A

yolk sac tumor

31
Q

elevated hCG and AFP

A

mixed tumor

32
Q

sheets of uniform polygnal cells with distinct cell bordersm lear glycogenrich cytoplasm

A

seminoma

33
Q

porrly differentiated pleomorphic cells in cords, sheets or papillary formation

A

embryonal

34
Q

cytotrophoblast and sychtiotrophoblast without villius

A

choriocarcinoma

35
Q

soft, well demarcated, grey white tumors

A

seminoma

36
Q

large- primitive looking cells with basophillic cytoplasm, indistince cell borders, and large nuclei with prominent nucleoli

A

embryonal carcinomas

37
Q

most common primary testicular neoplasm in kids under 3

A

tolk sac tumors

38
Q

structures resembiling orimitive glomeruli

A

yolk sac tumors

39
Q

firm masses with csts and cartilage

A

tertomas

40
Q

what age are tertomas malignant

A

post-puberty

41
Q

type of testicular cancer that mets early

A

nonseminomatous germ cell