Uterine Sarcomas Flashcards
1
Q
What are uterine sarcomas
A
- Rare tumours 150 cases/yr/UK
2
Q
Outline the categories of Uterine Sarcomas?
A
- Leiomyosarcoma (malignant fibroids)
- Endometrial stromal tumours (stroma beneath endometrium)
- Mixed mullerian tumours (derived from embryological elements of uterus)
3
Q
What are Leiomyosarcoma’s?
A
Malignant fibroids
4
Q
What are Endometrial Stromal Tumours?
Outline histological types
Who are they most common in?
A
Tumours of the stroma beneath endometrium
Histological types vary from **benign to highly malignant **
Perimenopausal women
5
Q
Whar are Mixed Mullerian Tumours?
Who are they most common in?
A
Derived from embryological elements of uterus
Most common in Elderly
6
Q
How do Uterine Sarcomas usually present?
A
Present:
- Irregular/ post-menopausal bleeding
- Leiomyosarcoma: rapid painful enlargement of fibroid
7
Q
Outline the treatment & prognosis for Uterine Sarcomas
A
Treatment: Hysterectomy + Radiotherapy/ Chemotherapy
Prognosis poor: 30% at 5yrs