USMLE VIROLOGY-3 Flashcards

1
Q

Questions

A

Answers

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2
Q

DNA viruses

A

HHAPPPy viruses!

Herpes
Hepadna
Adeno
Papova
Parvo
Pox
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3
Q

adenovirus basics

A

linear dsDNA

naked

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4
Q

adenovirus transmission

A

resp, ocular secretions

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5
Q

adenovirus sx

A

acute resp dz (ARD)
conjunctivitis
gastroenteritis

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6
Q

adenovirus vaccine

A

live nonattentuated
oral
used in military

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7
Q

papovaviruses include

A

HPV
BK
JC

PA/PO/VAviruses are all abbreviated!

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8
Q

JC virus causes

A

PML (progressive multifocal leukoencephalopathy)

esp in AIDS pts

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9
Q

herpesvirus basics

A

large dsDNA virus

enveloped

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10
Q

VZV transmission

A

resp secretions

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11
Q

chickenpox incubation

A

2w

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12
Q

varicella vaccine

A

live attenuated

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13
Q

EBV transmission

A

saliva, resp secretions

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14
Q

EBV associations

A

burkitt lymphoma
nasopharyngeal carcinoma
hairy oral leukoplakia (immunocompromised)

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15
Q

oncogene in burkitt lymphoma

A

c-myc

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16
Q

EBV cells on peripheral smear

A

atypical lymphocytes = activated T cells

foamy cytoplasm (Downy cells)

17
Q

Paul-Bunnell test

A

monospot

18
Q

blueberry muffin baby

A

deaf baby with hemorrhagic cutaneous lesions

congenital CMV

19
Q

HHV-6

A

causes “sixth disease” = roseola = exanthema subitum

20
Q

HHV-8

A

cofactor in Kaposi sarcoma

21
Q

poxviruses include

A

variola (smallpox)
molluscum contagiosum
cowpox

22
Q

umbilicated wart-like lesions

A

molluscum

23
Q

hepadnaviruses include

A

hepatitis B virus

24
Q

parvovirus (B19) basics

A

small ssDNA virus

25
Q

parvovirus causes

A

erythema infectiosum (fifth dz)
aplastic crisis
hydrops fetalis

26
Q

picornavirus basics

A

(+)ssRNA

naked

27
Q

picornaviruses include

A

PERCH on a “peak” (pico)

Polio
ECHO
Rhino
Coxsackie
Hepatitis
28
Q

poliovirus vaccine(s)

A
live attenuated (oral)
killed
29
Q

ECHO viruses

A

Enteric Cytopathic Human Orphan

infect GI tract, esp. in summer

aseptic meningitis, fever, rash, enteritis, common cold, hemorrhagic conjunctivitis

30
Q

coxsackie season

A

summer + fall

31
Q

coxsackie transmission

A

nasopharyngeal secretions

also fecal-oral

32
Q

hepatitis A caused by

A

enterovirus 72 (picornavirus)

33
Q

herpangina

A

coxsackie A

34
Q

hand-foot-and-mouth dz

A

coxsackie A